glipizide has been found to form inclusion complexes with β-cyclodextrin (β-cd) in solution and in solid state. the present study was undertaken to determine a suitable method for scaling up glipizide-β-cd inclusion complex formation and to evaluate the effect of some parameters on the efficiency of complexation. the solid inclusion complexes of glipizide and β-cd were prepared at a molar ratio...

background: metastasis is one the most leading cause of death from cancer. the chemokine receptor of cxcr4 has an important role in cell migration and cancer metastasis. additionally, metastasis is always associated with the process of epithelial-mesenchymal transition (emt). in this study the correlation between expression of cxcr4 and emt-tfs has been examined. methods: the expression of cxcr...

objective: the goal of this study is to evaluate the efficacy of intraperitoneal (jp) cisplatin as consolidation treatment, in epithelial ovarian cancer patients with pathologically negative surgical reassessment, following first-line platinum-based chemotherapy. methods: this study included 22 patients with figo stage (iic- iv) epithelial ovarian cancer (eoc) which had no evidence of disease a...

epithelial myoepithelial carcinoma is a rare biphasic low grade neoplasm of salivary glands; it most commonly occurs in the parotid gland but can also arise in minor salivary glands. here a case of 58-year-old female presented with left cheek swelling of one-year duration. ct scan revealed a localized submandibular salivary gland tumor mass not involving surrounding tissues. histological examin...

The prevalence of vaginal cysts is uncertain since many go unreported but it estimated that 1 out 200 women have a cyst. We report case 23-year-old female with secondary infertility an incidental asymptomatic cyst, which was originally misdiagnosed as endometriotic performed the surgical treatment negative hysterolaparoscopic findings, only to identify paravaginal sebaceous cyst on exploration....

radiography is one of the most valuable diagnostic tools used in comprehensive dental care. although there is no safe level of radiation exposure, the possible risk associated with exposure to radiation, must be elucidated. to date, a variety of assays have been proposed to assess the mutagenic potential of genotoxicants; however, these methods are typically laborious and time consuming. the ai...

stem cells located at the limbus ,  are the ultimate source for regeneration of the corneal epithelium in the normal and traumatized states.  when limbal stem cells are dysfunctional or deficient, limbal stem cell deficiency (lscd) develops. its surgical management depends on laterality and severity of corneal-limbal involvement. conventional methods of stem cell transplantation are conjunctiva...

The cadherin/catenin complex serves as an important structural component of adherens junctions in epithelial cells. Under certain conditions, beta-catenin can be released from this complex and interact with transcription factors in the nucleus to stimulate the expression of genes that regulate apoptosis and cell cycle control. While studying the effects of the bacterial pathogen Chlamydia trach...

Although there are numerous aetiologies for coccygodynia described in the medical literature, precoccygeal epidermal inclusion cyst presenting as a coccygodynia has not been reported. We report a 30-year-old woman with intractable coccygodynia. Magnetic resonance imaging showed a circumscribed precoccygeal cystic lesion. The removed cyst was pearly-white in appearance and contained cheesy mater...