Epithelioid angiosarcoma of the vagina is a rare variant, easily misdiagnosed as other epithelial neoplasms. On Hematoxylin-Eosin-stained sections, the pathologist encounters sheets of large, mildly to moderately pleomorphic epithelioid cells, with abundant eosinophilic cytoplasm, vesicular nuclei, and prominent nucleoli. We report the case of a 22-year-old woman initially diagnosed with condil...

Perivascular epithelioid cell tumors (PEComas) of gastro intestinal tract are very rare, with only few cases reported in the literature. The PEComas are a family of rare mesenchymal tumors characterized by perivascular epithelioid cell differentiation. We herein report our experience with a patient who had a primary gastric PEComa that was diagnosed by an expert pathologist review of the excise...

Abstract Epithelioid haemangioendothelioma (EHE) is a rare vascular soft tissue malignant tumour with unknown etiology; the estimated prevalence of EHE less than one in 1 million. A 56-year-old man was admitted our department due to pain right side abdomen lasting for two years and weight loss up 10 kg. Since 2012, patient underwent lung abdominal CT scanning as well biopsy, however diagnosis c...

We describe the case of a 67 year old female with longstanding uterine leiomyomas who presented with fatigue, weight loss, elevated CA-125 and an enlarging mass arising from the posterior uterine fundus. Histologic sections of the mass contained a leiomyoma with interspersed foci of malignant epithelioid cells forming anastomosing vascular channels. The neoplastic cells were diffusely positive ...

Angiomyolipoma (AML) is a type of tumor in the perivascular epithelioid cell neoplasm (PEComa) family. Epithelioid angiomyolipoma (EAML), having malignant potential, is considered a rare variant of angiomyolipoma. The most common site of EAMLs is kidney, and extra-renal EAMLs are very uncommon, with liver being the most common site.1 Other locations including retroperitoneum, uterus, liver, lun...

Epithelioid hemangioendothelioma is a rare vascular tumor with intermediate biologic behavior and metastatic potential. Primary renal epithelioid hemangioendothelioma is extremely rare and we present the second report of this rare tumor in an interesting clinical scenario. A 59-year-old male with established history of widely metastatic high grade esophageal adenocarcinoma was found to have an ...

BA: bacillary angiomatosis CEAN: cutaneous epithelioid angiomatous nodule EH: epithelioid hemangioma KS: Kaposi sarcoma PyG: pyogenic granuloma INTRODUCTION Cutaneous epithelioid angiomatous nodule (CEAN) is a recently described rare vascular proliferation. Although this neoplasm is more commonly reported as a solitary papule or nodule on the trunk or extremities, eruptive patterns have been re...

INTRODUCTION Epithelioid hemangioedothelioma (EHE) is a rare vascular tumor characterized by neoplastic proliferation of epithelioid or histiocytoid epithelial cells. EHE of bone constitutes <1% of primary malignant bone tumor. EHE in the skull is an extremely rare case. Here, we report a case of multiple neoplasm of the skull in a 15-month-old boy who presented with gradual facial swelling for...

Epithelioid sarcoma is a rare soft-tissue sarcoma which classically presents as a subcutaneous or deep dermal mass in distal extremities of adolescents and young adults. A more aggressive "proximal" or "large-cell" type has been described in rare cases to occur as a deep soft-tissue mass at proximal body sites which tends to recur and metastasize earlier than the conventional epithelioid sarcom...

Deciduoid mesothelioma is a rare variant of the epithelioid histotype spectrum, resembling decidua of gravid uterus. It is found in the peritoneum of young women, but also in the pleura of elderly people. Histotype plasticity from epithelioid to sarcomatoid mesothelioma may be considered as epithelial-mesenchymal transition (EMT). A full autopsy was performed and mesothelioma infiltrates were a...