BACKGROUND The increase in concentration of osteoprotegerin, an antagonist of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), in the peritoneal fluid of women with endometriosis may interfere with TRAIL-induced apoptosis in endometriotic cells and promote the development of endometriosis. In the present study, the effect of tunicamycin, a possible apoptosis enhancer, on TRAIL-i...

Important changes to the statutes of the European Society of Cardiology (ESC) were introduced on the occasion of the annual ESC congress in Vienna in September 2003. The Extraordinary General Assembly held at the annual congress approved massively the most important changes ever proposed to the constitution of the ESC over the last 20 years. These changes were necessary in order to offer the po...

Recent studies have shown that the RNA binding protein Musashi 2 (Msi2) plays important roles during development. Msi2 has also been shown to be elevated in several leukemias and its elevated expression has been linked with poorer prognosis in these cancers. Additionally, in embryonic stem cells (ESC) undergoing the early stages of differentiation, Msi2 has been shown to associate with the tran...

Extra sex combs (esc) is one of the Polycomb Group genes, whose products are required for long term maintenance of the spatially restricted domains of homeotic gene expression initially established by the products of the segmentation genes. We recently showed that the esc protein contains five copies of the WD motif, which in other proteins has been directly implicated in protein-protein intera...

Stem cell treatment may positively influence recovery and inflammation after shock by multiple mechanisms, including the paracrine release of protective growth factors. Embryonic stem cells (ESCs) are understudied and may have greater protective power than adult bone marrow stem cells (BMSCs). We hypothesized that ESC paracrine protective mechanisms in the heart (decreased injury by enhanced gr...

The product of the extra sex combs (esc) gene is required during embryogenesis for the correct determination of segments in Drosophila. If this product is absent, most segments develop like the normal eighth abdominal segment. Here, I extend previous results (Struhl, 1981a) showing that this phenotype results in large part from indiscriminate expression of the bithorax-complex genes which are n...

This study proposes and implements maximum power Point Tracking (MPPT) control on thermoelectric generation system using an extremum seeking control (ESC) algorithm. The MPPT is applied to guarantee maximum power extraction from the TEG system. The work has been carried out through modelling of thermoelectric generator/dc-dc converter system using Matlab/Simulink. The effectiveness of ESC techn...

In [22] a form of extremum seeking for control (ESC) was developed for the stabilization of uncertain nonlinear systems. In ESC the extremum seeker controls the systems through feedback rather than fine tuning a controller. The ESC results, and other related results, apply only to systems affine in control. However, in most physical systems the control effort enters the system’s dynamics throug...