objective: measurement of glomerular filtration rate (gfr) is the best determinant in assessment of kidney function for diagnostic and therapeutic purposes. as extremely accurate methods of gfr measurement (i.e. inulin clearance) are expensive and time-consuming and due to limitations of the 24 hour urine collection method, some formula have been developed for the gfr measurement. here we have ...

conclusions our results indicated a reversible increase in rbv bioavailability after telaprevir exposure, which might be linked to the impairment of the gfr. this also suggests a rbv-telaprevir pharmacological interaction, a possible source of severe anemia observed under triple therapy. these results suggest that rbv pharmacological monitoring may be clinically relevant, especially in the cont...

background elevated serum gamma-glutamyltransferase (ggt) is predictive of various cardiovascular (cv) risk factors including chronic kidney disease (ckd). elevated serum ggt has been recognized in smokers who are likely to develop ckd, but no study has focused on serum ggt and ckd in smokers. objectives the aim of this study was to clarify the associations between cigarette consumption, elevat...

conclusions: in this study, kidney transplant recipients with a lower ri and pi and a higher edv at 1week showed better graft function at 6 months after transplantation. results: fourteen patients (15.4%) had impaired graft function after 6 months (gfr less than 60 ml/min/1.73m2). multivariate linear regression analysis showed significant correlation between gfr at 6 months and ri, pi and edv w...

BACKGROUND The prevalence of chronic kidney disease (CKD) increases with age, and new glomerular filtration rate-estimating equations have recently been validated. The epidemiology of CKD in older individuals and the relationship between a low estimated glomerular filtration rate as calculated by these equations and adverse outcomes remains unknown. METHODS Data from the BELFRAIL study, a pro...