Twenty four farmed great sturgeon, Huso huso (including 8 males and 16 females) over 6 years old were used to develop a method for determination of sex and maturity stages. Seasonal gonadal tissue and blood samples were collected from farmed great sturgeon for three years. The sex and stages of maturity were determined by histology and laparoscopy at the beginning and end of experiment. Plasma ...

BACKGROUND Sex-related differences in the severity of multiple sclerosis (MS) could be influenced by the sex hormones. MATERIALS AND METHODS This cohort (historical) study evaluated the sex hormone levels during menstrual cycle and their correlation with disease severity in MS. RESULT Patients with MS had significantly lower testosterone, dehydroepiandrosterone sulfate and prolactin levels ...

Cytoplasmic fractions containing steroid hormone receptor were prepared from rat prostate and uterine tissues, incubated first with [(3)H]dihydrotestosterone or [(3)H]estradiol, and then with their respective target and non-target tissue chromatins. Only prostate and testis chromatin bound the dihydrotestosterone-receptor complex from prostate cytosol extensively. Similarly, uterine chromatin b...

Background In the present study the effects of a hydro-alcoholic saffron (Crocus sativus) extract on pituitary-ovary axis and folliculogenesis were investigated. The aim was to study the possible role of saffron in female fertility and thereby show its usefulness in treating infertility and reproductive disorders in females. MaterialsAndMethods The study consisted of 50 adult female Sprague daw...

women with mammary carcinoma, the concentrations of total radioactive estrogen and the individual radiometabolites estradiol and estrone, and an uncharacterized fraction (Ep), were determined in several body tissues. Specimens of mammary tissue, mammary tumor, abdominal fat, muscle, and skin were removed 30 minutes after the infusion of the radioactive hormone. The median concentration of radio...

The effects of estriol and estradiol on the plasma levels of cortisol- and thyroxine-binding globulin activity, and on the secretion rates of aldosterone and cortisol were studied in man. The metabolite estriol had no consistent or significant influence on plasma levels of the hormone-binding globulin activities; the hormone estradiol increased these binding capacities significantly, as expecte...

Thimet oligopeptidase (TOP) and prolyl endopeptidase (PEP) are neuropeptidases involved in the hydrolysis of gonadotropin-releasing hormone, a key component of the hypothalamic-pituitary-gonadal axis. GnRH is regulated in part by feedback from steroid hormones such as estradiol. Previously, we demonstrated that TOP levels are down-regulated by estradiol in reproductively-relevant regions of the...

Estrogens have been implicated in cancer at hormone-responsive sites, such as the breast, ovaries, endometrium and prostate. Because cows’ milk contains estrogens, some authors have suggested that its consumption may contribute to the risk of cancer at these sites. However, these reports do not recognize the complex mechanisms these cells possess to regulate estradiol levels. Hormone-responsive...