We report a case of ethylene glycol poisoning in 70-year-old man with headache and dysarthria. Blood tests showed marked increase the anion gap (29.8 mOsm/kg) osmotic (14 mOsm/kg). The estimated blood concentration was 86.8 mg/dL. Ethanol administered he underwent haemodialysis for 7 cycles, which discontinued on day 12. Fomepizole, competes alcohol dehydrogenase, is an effective treatment pois...

Kathryn Rosica of the Chemical Manufacturers Association raised an interesting point in her letter (EHP vol. 102, p. 1006). Neither the term "glycol ethers" nor the term "ethylene glycol ethers" strictly identifies a class of chemicals whose members all share a common distinctive toxicological profile. As Rosica correctly noted, "Higher molecular weight ethylene glycol monoethers that have been...

alcohol poisoning can result in metabolic acidosis, renal failure, blindness, central nervous system (CNS) injury, pulmonary edema, or death. Ethylene glycol is present in antifreeze solutions, deicing solutions, foam stabilizers, and chemical solvents. Methanol is a component of windshield-washing solutions, gas-line antifreeze solutions, solvents, and brake cleaners. Isopropanol is found in r...

It is thought of interest to. report a fatal case of poisoning caused by the ingestion of ethylene chlorohydrin. Cases of poisoning by this substance through the gastro-intestinal tract have not previously been recorded except for two deaths from drinking a solvent mixture containing 25% of ethylene chlorohydrin (Guithert, 1944). Ethylene chlorohydrin (glycol chlorohydrin, chloroethyl alcohol),...