Exercise is rewarding, and long-distance runners have described a runner's high as a sudden pleasant feeling of euphoria, anxiolysis, sedation, and analgesia. A popular belief has been that endogenous endorphins mediate these beneficial effects. However, running exercise increases blood levels of both β-endorphin (an opioid) and anandamide (an endocannabinoid). Using a combination of pharmacolo...

Dental professionals should be aware that methamphetamine (MA) use is on the rise in North America. MA is a potent central nervous system stimulant with limited therapeutic effects. The allure of this drug is its availability in many different forms that are relatively easy to make and distribute and inexpensive to purchase and that produce prolonged euphoria for the user. This euphoria results...

Digital journalism and its research have evolved significantly over the last twenty-five years. When first online media were installed on an experimental basis in mid-1990s, neither companies nor scientific observers expected them to transform way operates. However, very soon after these humble beginnings, a seemingly infectious euphoria spread among scholars who hoped rejuvenate democracy with...

Globally in healthcare, the focus is on designing and implementing national e-health solutions in an attempt to address key challenges that are plaguing healthcare delivery. However, despite the initial euphoria and notwithstanding the significant investments made, to date, many of these e-health solutions have yet to prove their success or have been complete failures. This paper presents the f...

the old Union song, “Which side are you on?”1 To paraphrase Huck, you don’t know about David Lodge without you have read Small World, a wonderful and zany romp through the academic conference circuit. There we met Morris Zapp, a thinly disguised Stanley Fish, professor of English at Euphoria State, an even more thinly disguised Berkeley. I read these lines as a new and quite untenured professor:

In the mid-1990s the idea of offering library users a large package of journals at less cost than purchasing subscriptions separately seemed too good an opportunity to be missed, not only for librarians but also for publishers. The advent of the " Big Deal " promised a glorious future for users of journals, for publishers and for librarians. Why has the dream gone sour? As one who has shared an...

Background: Because in today's societies, not only the nutritional role of plants and fungi is very high, but also the main basis of many drugs are plants and plant products, therefore one of the problems of clinical toxicologists is the toxicity of these products. Objective: This study aimed to define the prevalence, symptoms, complications, effective treatments, type of substance use, the c...

When Griffiths presented his report ‘Community Care Agenda for Action’ to the Secretary of State, directors of social services heaved sighs of relief as it appeared to be some kind of confirmation that those of us responsible for delivery of a complex range of services were in reality performing an impossible set of tasks. Griffiths lent support to our view that we were being asked ‘to make bri...