.. n.ofrlhut·lon or neutrophlls to the action or endotoxin on in the airways or anaesthetized guinea-pigs was -•••cu•·•n~ the extra"Yasatlon or E"Yans blue dye. Endotoxin •llhrrflfdtsJ caused a dose-dependent Increase ln mlcro"Yascular blue dye which was maximal arter 2S mln (p<O.OS). The Correspondence: Or T.W. Evans, Dept of Thoracic Medicine, National Heart and Lung Institute, Dovehouse Stre...

In a weak acid medium, some aminoglycoside antibiotics, such as kanamycin (KANA), gentamicin (GEN), tobramycin (TOB) and neomycin (NEO), or acid bisazo dye Evans Blue (EB) can only produce very weak resonance Rayleigh scattering (RRS) signals. However, when two agents react with each other to form ion-association complexes, the RRS intensity can be greatly enhanced and a new RRS spectrum with a...

Daptomycin is a lipopeptide antibiotic with strong bactericidal effects against Gram-positive bacteria and minor side effects on skeletal muscles. The type and magnitude of the early effect of daptomycin on skeletal muscles of rats was quantified by histopathology, examination of contractile properties, Evans Blue Dye uptake, and effect on the patch repair process. A single dose of daptomycin o...

During the course of routine pathological examinations of 9 rabbits injected with relatively large amounts of the dye T-1824 (Evans blue), which is used for the determination of total plasma protein (Gregersen, Gibson, and Stead) and which has also been employed in therapeutic attempts in experimental cancer re.search (Brunschwig, Schmitz, and Jennings; DuranReynals), a bilateral tumor of the a...

The dye-dilution method for the determination of plasma volume presents several problems, one of which is the estimation of dye concentration in plasma. It is with this problem that the present paper is primarily concerned. The most frequently used dye is Evans blue, T 1824. The colorimetric estimation of this dye in plasma is open to a number of possible errors, particularly those introduced b...

The effects of subarachnoid injection of blood on blood-brain barrier permeability to albumin was assessed in a rat model. Subarachnoid injection of blood caused a significant sixfold increase in Evans blue extravasation, whereas sham operation or NaCl injection had no effect. In addition, subarachnoid injections of arachidonic acid or FeCl2 increased blood-brain barrier permeability to Evans b...

This investigation describes a surgical approach for ligation of the middle cerebral artery (MCA) in the young rat and evaluates consequences of the occlusion with a neurologic exam for motor deficits, Evans blue test for blood-brain barrier leaks, and light microscopy for histologic changes after 3 days. Evans blue extravasation and the lesion were limited to cortex at the burr hole site in oc...

SUMMARY Groups of ovalbumin sensitised, subscorbutic guinea-pigs were subjected to various regimens for 8-10 weeks. Group 1 were given 0.25 mg/100 g body wt. cholesterol by mouth daily and were stressed with intraperitoneal injections of ovalbumin twice weekly. Group 2 received the cholesterol only and Group 3 were stressed only. Group 4 on the low vitamin C diet only acted as controls. Evans b...

The use of azo dyes is popular in different branches of industry. Discharge of colourants to surface water cause harmful environmental effects. The aim of the present study was evaluation of effectiveness of diazo Evans blue decolourization by two Pseudomonas strains and estimation of process byproducts toxicity. In static conditions, both tested strains removed more than 85 % of dye after 48 h...

To determine under what circumstances hypertension is associated with brain oedema, the specific gravity of the brain was measured in acutely hypertensive, renal hypertensive and spontaneously hypertensive rats. Maximum mean arterial pressure (MAP) in acute hypertension induced by intravenous amphetamine or bicuculline was 171 +/- 5 and 181 +/- 5 mmHg respectively. In spite of pronounced extrav...