BACKGROUNDS Previous studies have shown that diffusion-weighted cardiovascular magnetic resonance (DW-CMR) is highly sensitive to replacement fibrosis of chronic myocardial infarction. Despite this sensitivity to myocardial infarction, DW-CMR has not been established as a method to detect diffuse myocardial fibrosis. We propose the application of a recently developed DW-CMR technique to detect ...

BACKGROUND Assessment of diffuse right ventricular (RV) fibrosis is of particular interest in pulmonary hypertension (PH) and heart failure (HF). Current cardiovascular magnetic resonance (CMR) T1 mapping techniques such as Modified Look-Locker inversion recovery (MOLLI) imaging have limited resolution, but accelerated and navigator-gated Look-Locker imaging for cardiac T1 estimation (ANGIE) is...

Introduction: Electrical cardioversion (ECV) is a safe method for the treatment of atrial fibrillation. It seems that left atrial volume index (LAVI) could be a good marker in predicting the success of ECV. The purpose of this study is to assess of the significance of LAVI measurement before ECV in predicting the recurrence of the AF. Methods: Fifty-one patients with AF, selected for ECV were s...

 Abstract Reactive soft tissue lesions are common in the oral cavity. These lesions usually occur as a painless non-neoplastic proliferation. Surgical excision of these lesions will cause aesthetic and mucogingival problems in the area. In this case, a prominent lesion in the anterior maxilla of a 40-year-old woman had recurred after two years. Surgical treatment was performed with complete ...

Background Cardiac involvement is a major risk factor for sudden death in patients with systemic sarcoidosis. Pathologically, cardiac sarcoid lesions can be classified as early (mainly lymphocytic, similar to lymphocytic myocarditis), intermediate (active granulomatous), and late phase (primarily scar). These pathological processes can affect the myocardial extracellular space volume (ECV) in c...

Background CMR is a useful tool for myocardial tissue characterization and to assess fibrosis and edema non-invasively. The estimation of extracellular volume fraction (ECV) is emerging as accurate biomarkers in many cardiac diseases associated with diffuse myocardial fibrosis. In this work, we present our automatic tool for ECV map creation. All the computational system consists of an executab...

Background T1 mapping and extracellular volume (ECV) measurements enable assessment of diffuse fibrosis in HCM and have been validated against histology. There still remains wide variation in pulse sequences used to measure T1 each with their associated limitations and biases in T1 determination. We sought to compare T1 values and ECV measurements between a 5(4R)3 variant of MOLLI and ShMOLLI i...

Background Myocardial fibrosis is associated with abnormal cardiac remodeling and poor prognosis in patients with hypertrophic cardiomyopathy. Currently, new cardiac MRI (CMR) techniques such as T1-mapping and extracellular volume (ECV) measurement are available to quantify diffuse myocardial fibrosis. We analyzed the size of myocardial fibrosis using preand post-contrast T1, ECV and late gadol...

Fro Ge He Sie infl La Ph Ma OBJECTIVES The purpose of this study was to prospectively investigate the diagnostic and prognostic impact of cardiac magnetic resonance (CMR) T1 mapping and validate it against left ventricular biopsies. BACKGROUND Extracellular volume (ECV) expansion is a key feature of heart failure. CMR T1 mapping has been developed as a noninvasive technique to estimate ECV; how...

BACKGROUND In hypertrophic cardiomyopathy (HCM), autopsy studies revealed both increased focal and diffuse deposition of collagen fibers. Late gadolinium enhancement imaging (LGE) detects focal fibrosis, but is unable to depict interstitial fibrosis. We hypothesized that with T1 mapping, which is employed to determine the myocardial extracellular volume fraction (ECV), can detect diffuse inters...