BACKGROUND Osteoarthritis (OA) of the hip is a major cause of functional disability and reduced quality of life. Management options aim to reduce pain and improve or maintain physical functioning. Current evidence indicates that therapeutic exercise has a beneficial but short-term effect on pain and disability, with poor long-term benefit. The optimal content, duration and type of exercise are ...

Objective(s): The goal of this study was assessing the prophylactic effect of exercise and its role as an adjuvant therapy on level of cytokines involved in angiogenesis in estrogen-dependent breast cancer. Materials and Methods: Forty female BALB/c mice were randomly assigned to exercise-tumor-exercise (ETE), exercise-tumor-rest (ETR), rest-tumor-exercise (RTE) and rest-tumor-rest (RTR) groups...

STUDY OBJECTIVES To determine whether long-term treatment with exercise therapy results in more favorable, disease-specific, health-related quality of life (HRQL) compared with short-term treatment with exercise therapy; and to determine whether there are gender differences in disease-specific HRQL among individuals randomized into the two treatment groups. DESIGN Randomized clinical trial. ...

The duration of action of single oral doses of 80 and 160 mg of propranolol during acute and sustained therapy was studied in nine patients with stable, exercise-induced angina pectoris. Plasma propranolol levels peaked 2 hours after both doses during acute and sustained therapy, but there were wide variations between individuals in plasma concentration with both dosage schedules. Plasma half-l...

OBJECTIVE Exercise therapy in heart failure (HF) patients is considered safe and has demonstrated modest reduction in hospitalization rates and death in recent trials. Previous cost-effectiveness analysis described favorable results considering long-term supervised exercise intervention and significant effectiveness of exercise therapy; however, these evidences are now no longer supported. To e...

The duration of action of single oral doses of 80 and 160 mg of propranolol during acute and sustained therapy was studied in nine patients with stable, exercise-induced angina pectoris. Plasma propranolol levels peaked 2 hours after both doses during acute and sustained therapy, but there were wide variations between individuals in plasma concentration with both dosage schedules. Plasma half-l...

Hemophilia is an X chromosome-linked inherited bleeding disorder. Frequent intra- articular and intra-muscular haemorrhage in severe haemophiliacs can cause significant disability. In order to resolve a simple bleeding in a 20-kilogram child, some 500 IV of factor VIII is usually required. The cost of this replacement therapy is enormous, especially for less wealthy countries. Vigorous exercise...

The duration of action of single oral doses of 80 and 160 mg of propranolol during acute and sustained therapy was studied in nine patients with stable, exercise-induced angina pectoris. Plasma propranolol levels peaked 2 hours after both doses during acute and sustained therapy, but there were wide variations between individuals in plasma concentration with both dosage schedules. Plasma half-l...

The duration of action of single oral doses of 80 and 160 mg of propranolol during acute and sustained therapy was studied in nine patients with stable, exercise-induced angina pectoris. Plasma propranolol levels peaked 2 hours after both doses during acute and sustained therapy, but there were wide variations between individuals in plasma concentration with both dosage schedules. Plasma half-l...