Article history: Received 8 June 2015 Accepted 8 June 2015 Available online 10 June 2015 such as the aorta, heart and brain as well as potentially deleterious hyperhomocystinemia in PES-positive subjects (for references see Slettedal et al., 2015). Such claims have independently been challenged by data from other centers, which also has spoken against a clinically significant, true association ...

PURPOSE Single nucleotide polymorphisms (SNPs) in the LOXL1 gene have been implicated in exfoliation syndrome (XFS) and exfoliation glaucoma (XFG). We have shown that these SNPs are not associated with the primary glaucomas such as primary open-angle (POAG) glaucoma and primary angle-closure glaucoma (PACG). To further establish the specificity of LOXL1 SNPs for XFS and XFG, we determined wheth...