The unmet need for the development of effective drugs to treat Alzheimer's disease has been steadily growing, representing a major challenge in drug discovery. In this context, repurposing, namely identification novel therapeutic indications approved or investigational compounds, can be seen as an attractive attempt obtain new medications reducing both time and economic burden usually required ...

celiac disease is a chronic, systemic and autoimmune disorder of gastrointestinal track that involves approximately 1% of individuals of all ages throughout the world. the collaboration of environmental factor such as gluten proteins and genetic factors, notably hla-dq2 and/or hla-dq8 trigger the disease. gluten-free diet is the simply and merely safe and proficient existing treatment. this art...

BACKGROUND The purpose of this study was to compare the efficacy of alginic acid alone versus alginic acid combined with low doses of pure glycyrrhetinic acid and bilberry anthocyanosides as an addon to conventional proton pump inhibitor therapy in relieving symptoms associated with nonerosive reflux disease. METHODS This prospective, randomized, 8-week, open-label trial was conducted at two ...