introduction: colorectal cancer (crc) is one of the most prevalent cancers in the world. genetic disorders and dietary habits play a part in crc. the most important cancer suppressor gene is p53. different mutations rates in 7th exon of p53 gene are reported in different areas  which may have a relationship with prognosis of crc. this study examines the relationship between mutation in 7th exon...

Three elastin peptides derived from a peculiar sequence (exon 30) were investigated by Infra-red spectroscopy (IRTF), differential scanning calorimetry (DSC) and dielectric (DDS) to clarify the relationship between structural organization physical properties of these in solid state. If great majority form organized structures, only few are able coacervate, one, that is encoded Exon 3...

Objective: Familial Mediterranean fever (FMF) is the most common disease that leads to secondary amyloidosis related persistent subclinical inflammation in Turkish patients. Pan-immune-inflammation value (PIIV), a recently-developed index validated predict prognoses of several malignancies. We investigated PIIV FMF Material and Methods: included 100 patients with regular follow-ups, defined as ...

acetyl-coenzyme a carboxylase α (acc-alpha) is considered as the key regulatory enzyme in fatty acid biosynthesis. acc-alpha gene is located on caprine chromosome 11 and is polymorphic in many goat breeds. in the current study, we aimed to find possible single nucleotide polymorphisms (snps) in the exon 1 region of the acc-alpha gene in iranian mahabadi goat breed. genomic dna was extracted fro...

background: multiple sclerosis (ms), a chronic inflammatory demyelinating disorder with neurodegenerative aspects, is more common among young adults, particularly women. methods: this molecular study was designed to investigate the il-7r α chain gene in iranian ms patients. we studied 60 ms patients, diagnosed based on 2005 r-mcdonald criteria and 60 apparently healthy individuals as the contro...