Nowadays, recommender systems are widely used in various domains to help customers access to more satisfying products or services. It is expected that exploiting customers’ contextual information can improve the quality of recommendation results. Most earlier researchers assume that they already have customers’ explicit ratings on items and each rating has customer’s abstracted context (e.g. su...

The continuous cohomology of Lie algebras of C-vector fields has been studied by I. M. Gelfand, D. B. Fuks, R. Bott, A. Haefliger and G. Segal in some outstanding papers [4], [9], [1]. B. L. Feigin [2] and N. Kawazumi [11], whose work is continued in [18], studied Gelfand-Fuks cohomology of Lie algebras of holomorphic vector fields Hol(Σ) on an open Riemann surface. Kawazumi calculated the coho...

In the paper (Hage and Verheij, 1999 [4], extending Verheij and Hage, 1997 [5]), we present an abstract model of the law that is based on two crucial characteristics of the law. The first characteristic is that the law is a dynamic system of states of affairs. The law evolves over time: regulations change, contracts are signed, property rights are acquired, etc. The second characteristic is tha...

The European Diagnostic Working Group presented comprehensive diagnostic algorithms for cystic fibrosis (CF) and confirmed the fundamental role of the sweat test for the diagnosis of CF. However, several important differences between well-accepted guidelines for sweat testing 3 and the recommendations of the Working Group need to be discussed. An adequate sweat sampling volume depends on the sa...

Background: Transcription factors regulate gene expression by interacting with their specific DNA binding sites. Some transcription factors, particularly those involved in transcription initiation, always bind close to transcription start sites (TSS). Others have no such preference and are functional on sites even tens of thousands of base pairs (bp) away from the TSS. The Cyclic-AMP response e...

introduction: cystic fibrosis (cf) is a common genetic disorder in white populations with an autosomal recessive pattern, caused by mutations in the cftr gene. the frequency of more than 1950 various mutations reported in the cftr gene significantly varies in different populations. ∆f508 is a common mutation in exon 10, which is first addressed in the molecular analysis of the disease. other ex...