OBJECTIVE In fragile X syndrome (FXS), it is hypothesized that absence of the fragile X mental retardation protein (FMRP) disrupts regulation of group 1 metabotropic glutamate receptor (mGluR and mGluR5)-dependent translation in dendrites. Lithium reduces mGluR-activated translation and reverses phenotypes in the dfxr mutant fly and fmr1 knockout mouse. This pilot add-on trial was conducted to ...

OBJECTIVE We aimed to develop a questionnaire for quantitative evaluation of the autonomy of public hospitals in China. METHOD An extensive literature review was conducted to select possible items for inclusion in the questionnaire, which was then reviewed by 5 experts. After a two-round Delphi method, we distributed the questionnaire to 404 secondary and tertiary hospitals in Guangdong Provi...

Over the past decade, the importance of acceptance of chronic pain has been demonstrated. Acceptance has often been assessed using the 20-item, two-factor Chronic Pain Acceptance Questionnaire (CPAQ; McCracken, Vowles, Eccleston, Pain 2004;107:159-66). This two-factor model has been supported but awaits further confirmation. The present investigation sought to address this issue in two large sa...

OBJECTIVE The current study investigated the internal structure and external relations of the Children's Psychological Processes Scale (CPPS). METHOD Principal components analysis and exploratory factor analysis were conducted. Concurrent validity studies were also completed with the Behavior Rating Inventory of Executive Function (BRIEF) and Woodcock-Johnson III Tests of Cognitive Abilities ...

OBJECTIVE The aim of this study was to develop a self-administered scale based on the special features of smartphone. The reliability and validity of the Smartphone Addiction Inventory (SPAI) was demonstrated. METHODS A total of 283 participants were recruited from Dec. 2012 to Jul. 2013 to complete a set of questionnaires, including a 26-item SPAI modified from the Chinese Internet Addiction...

INTRODUCTION Assessment environment, synonymous with climate or atmosphere, is multifaceted. Although there are valid and reliable instruments for measuring the educational environment, there is no validated instrument for measuring the assessment environment in medical programs. This study aimed to develop an instrument for measuring students' perceptions of the assessment environment in an un...

We explore the e ect of a form of question context on responses to a computer-mediated marketing research survey. As an increasing proportion of marketing research is conducted through computer interfaces, the pool of potential context e ects is rapidly expanding. We conduct an experiment using a multi-item scale that consists of ve dimensions and manipulate three such context e ects: whether a...

AIM The study aimed to develop two Japanese versions of King's Stigma Scale, a full version (KSS-J-1) and a short version (KSS-J-2), through psychometric property testing. METHODS The sample included 112 people with mental illness. We tested the constructs of the scales using both confirmatory and exploratory factor analyses. Internal consistency and test-retest reliability were tested. We ex...

Abstract Objectives The aim of this study was to conduct a multi-faceted assessment the psychometric properties Self-Compassion Scale (SCS). In addition goodness-of-fit, we aimed assess strength and replicability three factorial solutions, quality effectiveness scoring schemes scale (i.e., total score, two subscale scores, six scores). Methods Participants were 1508 Spanish-speaking community-d...