Submit Manuscript | http://medcraveonline.com Abbreviations: CT: Computed Tomography; MRI: Magnetic Resonance Imaging; RCT: Rotator cuff tears; AHI: Acromio Humeral Interval; AP: Anterior Posterior; AC: Acromio Clavicular; NSAIDs: Non-Steroidal Anti-Inflammatory Drug; ECM: Extra Cellular Matrix; ASCR: Arthroscopic Superior Capsule Reconstruction; CTA: Cuff Tear Arthropathy; RTSA: Reverse Total ...

The Extra cellular matrix (ECM) components are considered as good candidates for fabricating scaffolds with superior bioactivity or functionalizing biomaterials to improve their performance (Green, 2008). A biomimetic surface coating to improve or enhance the osteoconductivity of biomaterials and tissue engineering scaffolds holds great promise in orthopaedic and bone tissue engineering applica...

Introduction: Decellularization of tissues provides inductive extra-cellular matrices (ECM) for effective organ reconstruction: this promising approach has not been translated to breast reconstruction yet. 1, 2 We investigated the effectiveness of different decellularization protocols applied to porcine mammary glands with the purpose of developing an inductive biological matrix for prospective...

During angiogenesis, endothelial cell migration is coordinated by integrinmediated contact with the extra-cellular matrix (ECM), coupled with receptor tyrosine kinase signalling to regulate dynamic cytoskeletal and plasma membrane reorganization. A recent paper by Vitorino et al (2015) defined a new MAP4K4– moesin–talin–b1-integrin pathway that could be therapeutically exploited to suppress pat...

BACKGROUND Oral submucous fibrosis (OSF), a potentially malignant oral lesion, is a form of pathological fibrosis affecting the oral mucosa. It results from an imbalance in equilibrium of the normal process of synthesis and degradation of extra cellular matrix. Matrix metalloproteinases and its inhibitors play important role in remodeling of the extra cellular matrix which are important in prog...

Angiogenesis, the process of neovascularization from parent blood vessels, is a prerequisite for many physiological and pathological conditions that is regulated by a balance between the levels of endogenous angiogenic stimulators and matrix reloaded angiogenic regulators. Several non-collagenous carboxy terminal end domains in chains of type IV collagen matrix reloaded molecules selectively in...