Nasal type extranodal natural killer (NK) NK-cell/T-cell lymphoma (NKTCL) is a rare extranodal lymphoma of NK-cell or T-cell origin that most commonly affects immunocompetent middle-aged men of Asian or Native American descent [1]. The pathogenesis is not understood completely, but it is related in part to infection of the tumor cells with Epstein-Barr virus (EBV) [2]. Around 6-7% of all non-Ho...

Angioimmunoblastic T-cell lymphoma (AITL) is a frequent subtype of peripheral T – cell lymphoma (PTCL) characterized by generalized lymphadenopathy, hepatosplenomegaly, and frequent B symptoms. Extranodal manifestations are quite common in this subtype of Non Hodgkins Lymphoma which is characterized by frequent skin involvement. However, the extranodal disease should be evaluated thoroughly and...

Diffuse large B cell lymphoma (DLBCL) is the most common histologic subtype of Non-Hodgkin’s lymphoma (NHL), accounting for approximately twenty five percent of cases. Forty percent of patients with DLBCL present with the primary lesion in an extranodal site. The gastrointestinal tract is the most frequent site of extranodal lymphoma, with the stomach and intestines most often involved. Involve...

which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. A controversial conclusion regarding primary extranodal diffuse large B-cell lymphoma TO THE EDITOR: Recently, primary extranodal non-Hodgkin's lymphoma (NHL) has gained considerable attention. Many controversies are associated with primary extra-nodal NHL, ...

the gastrointestinal tract is the most frequently involved extranodal location for malt* lymphomas, but malt lymphomas of the large intestine are rarely observed. a treatment for colorectal malt lymphoma has not yet been established. in colonic malt lymphomas, the literature suggests that surgical resection of localized lesion may be the best choice. in the present case, combination of multi-ag...

Intravascular large B-cell Lymphoma (IVLBCL) is a rare subtype of extranodal non-Hodgkin’s lymphoma that challenging to diagnose and has poor prognosis. Here, we describe two patients newly diagnosed with IVLBCL at our institution: an African man hemophagocytic-syndrome-associated Italian woman cutaneous variant IVLBCL. They presented very different clinical manifestations. Both cases were in t...

We represent a rare case of lung adenocarcinoma accompanied by extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT). The patient was a 66-year-old male presented with 1 month history of recurrent cough and hemoptysis. Chest CT showed solitary ground-glass opacity (GGO) in the upper lobe of the right lung and mediastinal lymph node enlargement in station 3p. A CT-guided ...

Extranodal natural killer/T cell (NK/T cell) lymphoma (ENKTL), nasal type, is a rare non-Hodgkin lymphoma originating in the nasal cavity or in the paranasal sinuses. It can involve the skin, gastrointestinal tract, soft tissue, and testis, but involvement of breast is rare. Herein we report a case of extranodal NK/T cell lymphoma with bilateral breast involvement in a middle aged female. The u...

Precursor B-cell lymphoblastic lymphoma (B-LBL) is an uncommon subtype of Non-Hodgkin lymphoma (NHL), accounting for only 0.3% of NHL in adults and less than 10% of all LBL cases. Unlike T-cell LBL, it usually presents with extranodal involvement while sparing the bone marrow (BM). Among the 27 patients with LBL treated in the Asan Medical Center between January 2007 and March 2012, 3 had B-LBL...