Extracellular Vesicle Mimetics vesicles mimetics (EVMs) prepared from top-down approaches exhibit superiority both in production and biological properties as potential alternatives of extracellular (EVs). By extruding through membrane filters with decreased pore sizes, EVMs can be produced a large scale. In article 2200142, Chenhui Gu, Liqing Shangguan, Xianfeng Lin co-workers summarize the pre...

During cell division chromosomes are compacted in length by more than a hundred-fold. A wide range of experiments demonstrated that in their compacted state, mammalian chromosomes form arrays of closely stacked consecutive ~100Kb loops. The mechanism underlying the active process of chromosome compaction into a stack of loops is unknown. Here we test the hypothesis that chromosomes are compacte...

The cases of three patients with acute pulmonary oedema caused by inhalation of fumes from heated polytetrafluoroethylene (PTFE) in a plastic factory are described. One patient died from profound hypoxaemia and shock shortly after admission, and the other two patients survived after medical treatment. This is the first report of fatal pulmonary oedema in a worker exposed to PTFE heated in a pla...

Morgellons disease is a mysterious skin disorder that was first described more than 300 years ago. The disease Abstract is characterized by fiber-like strands extruding from the skin in conjunction with various dermatologic and neuropsychiatric symptoms. In this respect, Morgellons disease resembles and may be confused with delusional parasitosis. The association with Lyme disease and the appar...

Morgellons disease is a rare disease with unknown etiology. Herein, we report the first case of Morgellons disease in Korea. A 30-year-old woman presented with a 2-month history of pruritic erythematous patches and erosions on the arms, hands, and chin. She insisted that she had fiber-like materials under her skin, which she had observed through a magnifying device. We performed skin biopsy, an...

This paper discusses two common problems, “weld tenting” and low coating thickness over the external weld, and their causes in traditional three layer polyolefin pipeline coatings. To tackle these problems, a new approach to applying multilayer polyolefin coating to pipes is introduced. The new system consists of side-extruding high density polyethylene over a graded structure polyethylene (GSP...

The Adaptive Inverse Hyperbolic Tangent (AIHT) algorithm is capable of enhancing the global contrast of the original image adaptively, while extruding the details of objects simultaneously, cannot enhance local contrast. Therefore, we proposed a ContrastLimited Adaptive Histogram Equalization (CLAHE) modulation based on AIHT contrast enhancement algorithm from conjugate AIHT and CLAHE image con...