Jose Luis Sardina, Bruno Di Stefano, and Thomas Graf Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, USA; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA; Harvard Stem Cel...

Keywords: Bell polynomial Divided difference Faà di Bruno's formula Multicomposite function a b s t r a c t The well-known formula of Faà di Bruno's for higher derivatives of a composite function has played an important role in combinatorics. In this paper we generalize the divided difference form of Faà di Bruno's formula and give an explicit formula for the n-th divided difference of a multic...

378 Alternative Methods: 3Rs, Research and Regulatory Aspects Francesca Caloni 1, Patrizia Costa , Gianni Dal Negro 3, Isabella De Angelis 4, Silvia Dotti 5, Giovanna Lazzari 6, Giacomo Metteucci 7, and Augusto Vitale 8 Università degli Studi di Milano, Department of Health, Animal Science and Food Safety, Milan, Italy; Università degli studi di Milano, laboratory Animal Science and Medicine Sp...

The metabolism of flavone-8-acetic acid (FAA) has been hypothesized to be partly responsible for its potent anticancer activity in mice. The purpose of this study was to identify the mouse enzymes involved in FAA Phase I metabolism and evaluate their possible induction in vivo by FAA. Mouse microsomes metabolized FAA into 6 metabolites: 3',4'-dihydrodiol-FAA, 5,6-epoxy-FAA, 4'-OH-FAA, 3'-OH-FAA...

Facilitation and the niche: implications for coexistence, range shifts and ecosystem functioning Fabio Bulleri*, John F. Bruno, Brian R. Silliman and John J. Stachowicz Dipartimento di Biologia, Universit a di Pisa, Via Derna 1, Pisa 56126, Italy; Department of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27517, USA; Division of Marine Science and Conser...

Francesca Caloni 1, Giovanna Mazzoleni 2, Marisa Meloni 3, Chiara Urani 4, Maura Ferrari 5, Silvia Dotti 5 and Yula Sambuy 6 Università degli Studi di Milano, Department of Health, Animal Science and Food Safety (VESPA), Milan, Italy; Università degli Studi di Brescia, Department of Clinical and Experimental Sciences (DSCS), School of Medicine, Brescia, Italy; VitroScreen, In vitro research Lab...