نتایج جستجو برای: facial dysmorphism

تعداد نتایج: 60752  

2009
Ebru ARHAN Derya SOY Özlem ARMAN Zehra AYCAN Gülsen KÖSE

We report a female infant with facial dysmorphism, ectrodactyly, holoprosencephaly, and associated hypernatremia. A 7-month-old female infant with cleft lip and palate, and ectrodactyly was admitted to our hospital with recurrent hypernatremic dehydration. Magnetic resonance imaging revealed holoprosencephaly. Plasma osmolality was increased whereas urinary osmolality was decreased. Serum ADH l...

Journal: :Advanced materials 2013
Robert F Shepherd Adam A Stokes Rui M D Nunes George M Whitesides

A soft machine composed of a composite of elastomer and fibers resists puncture from sharp objects, and continues to operate even if punctured.

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2016
Jordan R Raney Neel Nadkarni Chiara Daraio Dennis M Kochmann Jennifer A Lewis Katia Bertoldi

Soft structures with rationally designed architectures capable of large, nonlinear deformation present opportunities for unprecedented, highly tunable devices and machines. However, the highly dissipative nature of soft materials intrinsically limits or prevents certain functions, such as the propagation of mechanical signals. Here we present an architected soft system composed of elastomeric b...

2010
Indrani S. Bhattacharya Marc Dweck Andrew Gardner Mark Jones Mark Francis

Isolated ventricular non-compaction cardiomyopathy (IVNC) is a rare, morphologically distinct primary genetic cardiomyopathy, which is now gaining prominence as an important differential diagnosis in patients presenting with cardiac failure. We describe a case report of a Nigerian male with facial dysmorphism presenting with cardiac failure. This is followed by a review of the literature with f...

2017

Hypoparathyroidism-Retardation-Dysmorphism (HRD) syndrome, also known as Sanjad Sakati Syndrome (SSS), is a rare autosomal recessive genetic condition seen in offspring of consanguineous parents of Middle Eastern origin. HRD consists of hypoparathyroidism leading to hypocalcemia and hyperphosphatemia, growth retardation, and characteristic dysmorphic features. This case presents a Saudi baby gi...

2016
Frederike Leonie Harms Katta Mohan Girisha Andrew A. Hardigan Anju Shukla Malik Alawi Ashwin Dalal Lauren Brady Lynne M. Bird Sophia Ceulemans Martina Bebin Susan M. Hiatt Edward J. Lose Michelle Primiano Wendy K. Chung Jane Juusola Zeynep C. Akdemir Matthew Bainbridge Wu-Lin Charng Mohammad K. Eldomery Ayman W. El-Hattab M. Saleh Stéphane Bézieau Benjamin Cogné Bertrand Isidor Sébastien Küry James R. Lupski Richard M. Myers Gregory M. Cooper Kerstin Kutsche

76 From a GeneMatcher-enabled international collaboration, we identified ten individuals with 77 intellectual disability, speech delay, ataxia and facial dysmorphism and a mutation in EBF3, 78 encoding a transcription factor required for neuronal differentiation. Structural assessments, 79 transactivation assays, in situ fractionation, RNA-seq and ChIP-seq experiments collectively 80 show that ...

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