This study aimed to examine the importance of fatigue as a clinical indicator in chronic obstructive pulmonary disease (COPD), by analysing its relationship with COPD severity and ability to predict risk of hospitalisation, and by comparing the intensity of fatigue in stable COPD patients with levels of fatigue reported by patients with other chronic conditions. We studied 100 consecutive patie...

INTRODUCTION Several differences have been reported in the clinical characteristics of chronic obstructive pulmonary disease (COPD) between men and women. Differences have been found in the association between respiratory symptoms and lung function, and in the factors associated with dyspnea. This raises the question of whether there are differences between the sexes in the relationship between...

It is commonly recognized that proinflammatory cytokines in patients with multiple sclerosis (MS) may increasingly cause inflammation. In this regard, the current study was aimed to shed light on the effectiveness of eight-week Pilates training program at interleukin-18 (IL-18) stage, severity of fatigue and balance as well as physical disability in females with MS. This study was a quasi-exper...

OBJECTIVE To assess the efficacy and safety of duloxetine in patients with chronic fatigue syndrome. METHODS A 12-week, randomized, double-blind study was designed to compare duloxetine 60-120 mg/d (n = 30) with placebo (n = 30) for efficacy and safety in the treatment of patients with chronic fatigue syndrome. The primary outcome measure was the Multidimensional Fatigue Inventory general fat...

Objective—To examine the relation between fatigue, disease activity, damage, and quality of life measures in patients with systemic lupus erythematosus (SLE). Methods—Consecutive patients attending the University of Toronto Lupus Clinic were studied. Disease activity was assessed using the SLEDAI and SLAM-R and damage using the SLICC/ACR Damage index. Fatigue was measured by the Fatigue Severit...

OBJECTIVE To assess whether liver transplant recipients have a hypoactive (sedentary) lifestyle and whether the level of everyday physical activity is related to complaints of fatigue. In addition, we explored the relationship between activity level and health-related quality of life. DESIGN Case comparison. SUBJECTS Eight persons 6-36 months after liver transplantation with varying severit...

Health-related quality of life (HRQoL) is impaired in HIV/HCV-coinfected patients (HIV/HCV) and further decreased by interferon (IFN)-based therapies. We aimed to investigate the impact of IFN- and ribavirin (RBV)-free therapies on HRQoL and fatigue.Thirty-three HIV/HCV-coinfected patients who underwent HCV therapy with sofosbuvir in combination with daclatasvir or ledipasvir were retrospective...

OBJECTIVES To compare the content of the Fatigue Severity Scale and the subscale "subjective experience of fatigue" of the Checklist Individual Strength, and (ii) to assess the reliability of both questionnaires in polio survivors. DESIGN Repeated-measures at a 3-week interval. SUBJECTS Consecutive series of 61 polio survivors. METHODS Concepts contained in the questionnaire items were li...

Fatigue is commonly associated with cancer and its therapy. The assessment of fatigue became increasingly important in cancer patients, as clinical interview may not indicate the severity of fatigue. Subjective assessment of fatigue in multi-dimensions indicates the level of severity of fatigue clearly to therapist, and the scores can be used to monitor response to cancer therapy. This study sh...

AIM to assess the effect of breathing exercises on fatigue level of the patients with COPD. METHODS this quasi-experimental research was conducted on 60 COPD patients hospitalized at hospitals affiliated to Tehran University of Medical Sciences. The subjects were randomized into "experience" and "control" groups. Data were gathered by interview and data registration from the files. The data g...