Histone deacetylase 8 (HDAC8) was originally classified as a Zn(II)-dependent deacetylase on the basis of Zn(II)-dependent HDAC8 activity in vitro and illumination of a Zn(II) bound to the active site. However, in vitro measurements demonstrated that HDAC8 has higher activity with a bound Fe(II) than Zn(II), although Fe(II)-HDAC8 rapidly loses activity under aerobic conditions. These data sugge...

metals bioaccumulation in five organs of cirrhinus  mrigala , labeo  rohita and catla catla captured from three industrial and sewage polluted downstream sites (shahdera = b, sunder = c and balloki = d) were compared with a non-industrial upstream site (siphon = a) during high (post monsoon) and low (winter) flow seasons of river ravi. mean concentrations of metals were significantly higher in ...

A simple and low cost chemosensor is described. This sensor could simultaneously detect three biologically important metal ions through fluorogenic (Zn(2+)) and chromogenic (Fe(2+), Cu(2+), and Zn(2+)) methods in aqueous solution. The sensor could function as a "turn-on" fluorescence receptor only to Zn(2+) ions. In addition, the sensor could be successfully applied to the detection of intracel...

Measurements of Pb, Cu, Zn, As, Ni, Hg, and Fe heavy metals and major elements and components such as Ca, HCO3, SO4, Na, K, Mg and Cl in soluble rain fractions were performed on rainwater collected at Arak plain during the rainy seasons of 2012. Concentrations of the heavy metals in the soluble fractions decreased for Fe, Pb, Zn, Ni, Cu, As and Hg, respectively and the major elements and compon...

Zinc (Zn) and iron (Fe) deficiencies are well-documented public health issue and an important soil constraint to crop production. Generally, there is a close geographical overlap between soil deficiency and human deficiency of Zn and Fe, indicating a high requirement for increasing concentrations of micronutrients in food crops. Breeding new plant genotypes for high grain concentrations of Fe a...

BACKGROUND It is estimated that 60% of pregnant women worldwide are anemic. OBJECTIVE We aimed to examine the influence of iron status on iron absorption during pregnancy by measuring supplemental iron absorption, red blood cell iron incorporation, and iron status in pregnant women. DESIGN Subjects were 45 pregnant Peruvian women (33+/-1 wk gestation), of whom 28 received daily prenatal sup...

The objective of this study was to determine the concentrations of Fe, K, Na, Ca, P, Zn and Mg in colostrum and mature milk (2 months) from nursing mothers, and the correlation between the concentration of these micronutrients and newborn weight, maternal age, gestational age GA, inter-pregnancy interval, and gestational weight gain. Thirty one women donated milk on the 2nd postpartum day and o...

The sardine (Sardina pilchardus) is the most popular species for fishing of the Algerian coast. Five toxic metals zinc (Zn), cadmium (Cd), copper (Cu), lead (Pb), and iron (Fe) that can affect human health are studied in this fish. Samples are collected monthly between January and December 2019 in the Ghazaouet bay. The collected samples were analyzed by atomic absorption spectrophotometry by s...