Satu kes feline panleukopenia dalam seekor kucing rumah berumur 18 bulan adalah dilaporkan. Tanda-tanda klinik utama ialah tidak berselera makan, kemasyghulan, ceret dan kekeringan badan. Perubahan-perubahan patologi yang biasa seperti atrofi vilus dan erosi pada epithelia usus kecil telah ditemui. Pemeriksaan najis menggunakan mikroskop lektron telah menunjukkan benda-benda yang menyerupai par...

The genetic trajectory leading to viral attenuation was studied in a canine parvovirus (CPV) strain grown on dog kidney cells for 115 transfers. Consensus sequences of viral populations at passages 0, 3, 30, 50, 80, and 115 were obtained from PCR products covering 86% of the genome; clones from each of the 80th and 115th passages were also sequenced, covering 69% of the genome. Sixteen changes ...

Canine parvovirus (CPV) is an emerging DNA virus that was first observed to cause disease in canines in 1978 and has since become a ubiquitous pathogen worldwide. CPV emerged from feline panleukopenia parvovirus (FPLV) or a closely related virus, differing at several key amino acid residues. Here we characterize the evolutionary processes underlying the emergence of CPV. Although FPLV has remai...

Canine parvovirus (CPV) and feline panleukopenia virus (FPV) differ in their ability to infect dogs and dog cells. Canine cell infection is a specific property of CPV and depends on the ability of the virus to bind the canine transferrin receptor (TfR), as well as other unidentified factors. Three regions in the capsid structure, located around VP2 residues 93, 300, and 323, can all influence c...

Canine parvovirus (CPV), first recognized as an emerging virus of dogs in 1978, resulted from a successful cross-species transmission. CPV emerged from the endemic feline panleukopenia virus (FPV), or from a closely related parvovirus of another host. Here we refine our current understanding of the evolution and population dynamics of FPV and CPV. By analysing nearly full-length viral sequences...

BACKGROUND Feline Panleukopenia (FPL) is a serious disease of cats that can be prevented by vaccination. Kittens are routinely vaccinated repeatedly during their first months of life. By this time maternally derived antibodies (MDA) can interfere with vaccination and inhibit the development of active immunity. The efficacy of primary vaccination under field conditions was questioned by frequent...

Feline Pan-leukopenia is an important deadly gastrointestinal disease of cats. It mostly prevalent in kittens with declining maternal antibodies as well unvaccinated Vitamin D and E, glutathione peroxidase superoxide dismutase are essential enzymatic non-enzymatic components defensive system involve defending the body against oxidative radicals. Malondialdehyde a reliable commonly used marker o...