Primary retroperitoneal mucinous cystadenocarcinoma is an extremely rare tumor. Preoperative diagnosis is very diffi cult and the treatment remains controversial. A 37-year-old Korean woman (gravida 0) presented with a huge abdominal mass. Computed tomography scan revealed an 18 × 11 cm sized unilocular cyst with irregular wall thickening and solid component at right adnexa. Serum CA 19-9 was s...

INTRODUCTION Young cancer patients increasingly request fertility sparing alternatives to their cancer treatments, which they should be offered when allowed so by the risk-benefit balance and after obtaining informed consent. CASE PRESENTATION Here, we report the case of a 25 year-old nulliparous patient who presented with a synchronous endometrioid ovarian and endometrial carcinoma. She was ...

Extraovarian yolk sac tumor (YST) is an extremely rare malignancy occurring mainly in girls and young women of childbearing ages and commonly treated with fertility-sparing surgery and postoperative adjuvant chemotherapy. We report a case treated with neoadjuvant chemotherapy (NACT) followed by cytoredutive surgery and adjuvant chemotherapy. A 32-year-old single woman came for a second opinion ...

There is a general trend towards delay in childbearing age amongst women. The ovarian reserve clearly falls with increasing age and the impact is greater with advancing age, particularly from late 30s. Presence of other risk factors can increase the risk of subfertility. A large number of women are exposed to pelvic surgery for various reasons, both elective and emergency. There is evidence tha...

BACKGROUND To retrospectively investigate reproductive outcomes after fertility-sparing surgery and postoperative adjuvant chemotherapy in malignant ovarian germ cell tumors (MOGCT) and sex cord-stromal tumors (SCST). METHODS Data from 32 MOGCT (6 dysgerminomas, 6 yolk sac tumors, 17 immature teratomas, and 3 mixed germ cell tumors) and 9 SCST (4 granulosa cell tumors and 5 sertoli-leydig cel...

OBJECTIVE To evaluate the clinicopathologic characteristics and prognostic factors of ovarian granulosa cell tumors. METHODS Medical records of 113 patients presenting between January 1995 and December 2007 were retrospectively reviewed. RESULTS One-hundred two patients had adult type disease, with a mean age of 46.2 years (range, 18 to 83 years) and a mean follow-up period of 54.7 months (...

OBJECTIVES Radical trachelectomy has emerged as a reasonable fertility-sparing operation for selected patients with stage I cervical cancer. The purpose of this report is to describe our technique of radical abdominal trachelectomy, a fertility-sparing operation in women with cervical cancer, and review the current literature on this procedure. METHODS A review of a prospectively maintained d...

At present there are various strategies to protect fertility potential against the possibly harmful effects of cancer therapy. Options range from newly emerging pharmacological treatments (e.g. ovarian suppression, apoptotic inhibitors) to cryopreservation techniques (e.g. embryo, oocyte, ovarian tissue). Surgical interventions for cancer treatment may directly or indirectly harm future fertili...