Maternal fetal leakage (FMH) is a well-known cause of anemia. We define it as the transition erythrocytes into maternal circulation. Its severity determined by measuring level hemoglobin in mother's blood using Kleinhauer-Betke test or cytometric method (FCM). The paper presents case newborn with massive maternal-fetal leakage. Kleinhauer result was greater than 5% cells, and initial neonatal 3...

Placental chorioangiomas greater than 4 cm in diameter are rare placental tumors. They have adverse fetomaternal outcomes. We present our experience with two cases having a giant angioma and review the relevant literature.

BACKGROUND Antepartum hemorrhage (APH) contributes significantly to maternal and perinatal morbidity and mortality globally, particularly in the developing world like ours. Prevention, early detection, and prompt management cannot be overemphasized to significantly reduce the morbidity and mortality associated with this condition. OBJECTIVES The study is aimed at determining the prevalence, e...

The concept of compatibility is dependent on the specifity of immune responses. The immunology of reproduction, and in particular the tolerance of two genetically distinct organisms and their fruitful symbiosis, is one of the most imposing paradoxes in immunology. In normal human pregnancy, the allogeneic embryo is tolerated by the maternal immune system for about 40 weeks without general immun...

OBJECTIVES To analyze the role of middle cerebral artery (MCA) peak systolic velocity (PSV) in the prediction of severe fetomaternal hemorrhage (FMH) and to compare it with standard biophysical assessment. DATA SOURCES Retrospective review of cases of FMH seen in our unit and systematic review of the literature. RESULTS We followed the MOOSE guidelines to review the literature. From 838 art...

OBJECTIVE To determine maternal outcome as antenatal and postnatal complications and neonatal outcome as birth weight, morbidity and mortality in triplet gestation. STUDY DESIGN Observational study. PLACE AND DURATION OF STUDY Mother and Child Health (MCH) Centre, Pakistan Institute of Medical Sciences, Islamabad from May 2000 to April 2006. PATIENTS AND METHODS All the patients with trip...

BACKGROUND NO and NO synthases (NOS) play an important role in the physiology of the fetomaternal blood circulation, although their expression in pathological conditions is unclear. Intrauterine growth retardation (IUGR) is a disorder most probably caused by abnormality of the fetomaternal bloodflow. MATERIALS AND METHODS The expression of endothelial NOS (ecNOS) from arteria umbilicalis and ...

Several designs and analytical approaches have been proposed to dissect offspring from maternal genetic contributions to early-onset diseases. However, lack of parental controls halts the direct verification of the assumption of mating symmetry (MS) required to assess maternally-mediated effects. In this study, we used simulations to investigate the performance of existing methods under mating ...