The evaluation of liver fibrosis is critical, particularly to rule out cirrhosis. Novel non-invasive tests such as transient ultrasound elastography are widely used to stage liver fibrosis as an alternative to liver biopsy, and this technology has recently been approved in the US. In this review, we discuss the performance characteristics of elastography for a variety of liver diseases and high...

Progressive hepatic fibrosis with the development of cirrhosis is a feature of almost all chronic liver diseases. Liver biopsy is currently considered the gold standard for assessing hepatic fibrosis. However, it is an invasive and painful procedure, with rare but potential life threatening complications, limiting its acceptance and repetition in usually asymptomatic patients.1,2 ABSTRACT REZUM...

Abstract BackgroundAmong non-invasive strategies available for liver fibrosis assessment, transient elastography is widely used, as it and can be repeated. Hepatus® (Mindray, China) one novel instrument measuring stiffness that now in the market with lower price than its precursor, FibroScan® (Echosens, Paris). MethodIn this cross sectional study, CHB patients single center were recruited conse...

Background: Liver stiffness measurements can be used to assess liver fibrosis and acquired by transient elastography using FibroScan ® with Acoustic Radiation Force Impulse imaging. The study aimed establish measurement scores in a chronic hepatitis C cohort explore the correlation agreement between factors influencing agreement. Methods: Patients had FibroScan® (right lobe of liver) left liver...

BACKGROUND Liver fibrosis remains one of the most important predictors of sustained virological response (SVR) in this era of direct-acting antiviral treatment of chronic hepatitis C. We compare non-invasive fibrosis assessment with liver biopsy (METAVIR) in terms of their ability to predict SVR by telaprevir (TVR)-based triple therapy. METHODS This prospective study consisted of 108 patients...

At present, liver transplantation remains the only curative option for the patients with cirrhosis and end-stage liver diseases. The survival rate and recurrent diseases remain the major issues in the patient post-transplantation. Unani medicine is one of the oldest traditional systems of medicine which has been treating chronic liver diseases and cirrhosis (Talayyaful-Kabid) for centuries. The...

Liver stiffness was measured by transient elastography (FibroScan) in 228 consecutive patients with chronic viral hepatitis, with (115) or without cirrhosis (113), to study its correlations with serum transaminases [alanine aminotransferase (ALT)], fibrosis stage and surrogate noninvasive markers of fibrosis (APRI, FORNS, FibroTest and hyaluronic acid). The dynamic profiles of serum transaminas...

OBJECTIVE The aim of our study was to assess a possible association between plasma inflammatory biomarkers (CRP, IL-6, soluble CD14) and the extent of fibrosis or cirrhosis using a FibroScan® in HIV/HCV co-infected patients. METHODS This cross-sectional study assessed 60 HIV/HCV co-infected patients who had paired plasma samples and FibroScan® values available. All included patients were cont...

BACKGROUND AND AIMS Despite the high prevalence of chronic hepatitis B (CHB) in Africa, few studies have been performed among African patients. We sought to evaluate liver stiffness measurement by FibroScan® (LSM) and two biochemical scores (FibroTest®, Fibrometer®) to diagnose liver fibrosis in Senegalese CHB patients with HBV plasma DNA load ≥3.2 log(10) IU/mL and normal alanine aminotransfer...