Old George sat on an upturned half-barrel cleaning his gun. It only ever shot blanks these days, but that didn't matter much. A fellow outlaw'd once told him the state of your gun's soul and liked sound religion as much any other he'd come across. Least it had clarity; was sure.Around corner from phony saloon he up front came sounds horses yelling. The director telling someone to fall bigger—bi...

Wounds, due to their complexity, end up impairing the functioning of skin, causing disability or loss function, in some cases, they can affect patient’s general condition, especially when not properly treated, which lead severe infections sepsis and individual death. Symptoms such as low self-esteem, lack motivation, social work changes, deficits quality life changes self-image also be attribut...

The use of prophylactic antibiotics in the initial treatment of noninfected dog bite wounds is controversial. All patients with noninfected dog bite wounds who presented to our emergency department (ED) over a two-year period were considered for entry into a randomized prospective study. Patients were excluded from the study if they had any high-risk criteria for infection: puncture wounds, han...

BACKGROUND Bacterial infections of wounds impair healing and worsen scarring. We hypothesized that transcriptome analysis of wounds infected with Klebsiella pneumoniae (K.p.) or Pseudomonas aeruginosa (P.a.) would indicate host-responses associated with the worse healing of P.a.- than K.p.-infected wounds. METHODS Wounds created on post-operative day (POD) 0 were infected during the inflammat...

UNLABELLED Introduction. Silver dressings are widely used in the treatment of chronic wounds to reduce bacterial bioburden. However, little is known about the mechanism of silver ions on the healing process. In this study, a mouse model of wound healing was used to examine the effect of silver dressings in normal and diabetic wounds. METHODS Two 5-mm full-thickness wounds were created on t...

Background: The process of wound healing involves integrated events including inflammation, granulation tissue formation, matrix deposition and remodeling. Growth factors play a key role in the process. Among them transforming growth factor-ß1 (TGF-ß1) is known to accelerate tissue repair by promoting the synthesis and deposition of extracellular matrix proteins. However, persistence or overact...

Many patients present with wounds which are bleeding or prone to bleeding, and so cannot be treated with a noninteractive dressing. These wounds include: 8 Partialand full-thickness wounds 8 Arterial and venous ulcers 8 Diabetic foot ulcers 8 Pressure ulcers 8 Fungating lesions 8 Post-surgical wounds 8 Toe nail avulsions 8 Donor sites 8 Traumatic wounds 8 Wounds post debridement (sharp, surgica...

background and purpose: vitamin c is administered orally or intravenously for the treatment of burn wounds. however, effects of the topical application of vitamin c remain unclear. this study aimed to evaluate the effects of topical vitamin c solution on the necrotic tissue volume of second-degree burn wounds. methods: this clinical trial was conducted on 30 patients with second-degree burns ad...

background: this study was designed to investigate the efficacy of pentoxifylline (ptx) in the treatment of irradiated wounds. materials and methods: ten female pigs of the large white strain were used in these investigations. six skin fields, 4 * 4 cm and separated from each other by 4 cm, were marked out on each flank and those on left flank were irradiated with 18gy single dose of 250 kv x-r...

results: patients in the case and control groups were similar in age and admission vital signs. during the second operation, the bleeding volumes measured in the case and control groups were 66 ± 27.01 ml and 152 ± 85.4 ml, respectively. there was some pad-induced damage after the removal of the pad in the control group. patients and methods: twenty male patients with grade iv or v liver injuri...