The aim of this work was to develop a pulsatile release system with metoprolol for chronotherapeutical use by coating swellable mini-tablets with Eudragit RS. To study the influence of the formulation factors (amount of coating polymer, plasticizer percentage in film coating and swelling agent percentage in mini-tablets), a Box-Behnken design of experiment (DoE) was used. To evaluate the influe...

The aim of this study was to formulate a film-coated Valsartan/Amlodipine (VS/AM) immediate release tablets and to evaluate their in vivo release profile. VS/AM core tablets were manufactured using dry granulation method. Opadry aqueous coating dispersion was used as film coating material. Dissolution of the film coated tablets was tested in 900 ml of 0.5% SLS media, bioequivalence of tablets w...

Evaporated optical coatings fabricated from hafnium dioxide and silicon dioxide are the standard approach for high-peak-power laser components due to the high laser damage resistance of such coatings and the ability to deposit on largeaperture substrates. The tensile film stresses of such coatings may lead to failure, however, particularly in low-relative-humidity purged or vacuum use environme...

Abstract The main objective of this study was to prepare colon-specific pellets of budesonide using pectin as film coating.  Pellet cores of budesonide were prepared by extrusion / spheronization technique. Pectin, in different ratios was combined with Eudragit RS30D, Eudragit NE30D or Surelease to produce film coating. The dissolution profiles of pectin coated pellets were investigated in pH o...

The industrial practice of curtain coating, used in a vast number of applications, involves a liquid film falling vertically to coat a solid surface passed underneath at high speed. This solid surface may either be dry prior to reaching the liquid film making contact or be pre-wetted by a thin liquid film, depending upon the nature of the application. Above some critical speed, dependent upon t...

Thin film coatings are used to reduce the generation of secondary electrons at the ends of the Advanced Photon Source (APS) rf cavity tuners because these electrons result in increased temperatures on the tuner. To improve the film properties over the existing evaporated titanium film, a magnetron-sputtered film of titanium nitride has been developed that is both harder and adheres more strongl...

This work is aimed to evaluate the role of nanoclay in the protective performance of an eco-friendly silane sol-gel layer applied on mild steel substrate in 0.1M sodium chloride solution. At the first step, the effect of pH of the silane solution, consisting of a mixture of γ-glycidoxypropiltrimethoxysilane and methyltriethoxysilane and tetraethoxysilane, on the coating performance was evaluate...

A hydrogel-based dual film coating is electrofabricated for transducing bio-relevant chemical information into electronical output. The outer film has a synthetic biology construct that recognizes an external molecular signal and transduces this input into the expression of an enzyme that converts redox-inactive substrate into a redox-active intermediate, which is detected through an amplificat...

The target was to study and develop industrially suitable methods to apply thermoplastic coatings on plywood. Typically, wear and climatic resistance for wooden sheets, such as chip board and plywood, is achieved by thermosetting resin coating (e.g. phenolformaldehyde). However, economical and environmental issues are driving towards thermoplastic coatings (e.g. polyethylene) in such products. ...

chromate conversion coating is applied on aluminum 6061. the optimum conditions for chromate bath composition and immersion time are also obtained for standard requirements provision such as corrosion resistance in salt spray test, electrical resistance and coating quality. the applied coatings are electrochemically tested in sea and distilled water. according to tafel and cyclic polarization c...