Our patient was worked up for mild developmental delay associated with focal scalp alopecia at age 6, and was diagnosed with encephalocraniocutaneous lipomatosis (also known as Haberland or Fishman syndrome), a rare neurocutaneous syndrome characterized by skin lesions (most commonly focal alopecia with or without underlying lipoma), ocular lesions, and CNS anomalies. CNS anomalies are usually ...

Justin Lessler*, Derek A. T. Cummings, Steven Fishman, Amit Vora and Donald S. Burke Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street E5537, Baltimore, MD 21205, USA Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 DeSoto Street, Pittsburgh, PA 15261, USA Department of Biostatistics, Johns Hopkins Bloomberg School of Public Healt...

9 Pritchard KI, Thomson DM, Myers RE, Sutherland DJA, Mobbs BG, Meakin JW. Tamoxifen therapy in premenopausal patients with metastatic breast cancer. Cancer Treat Rep 1980;64:787-96. 10 Fishman LM, Liddle GW, Island DP, Fleischer N, Kuchel 0. Effects of aminoglutethimide on adrenal function in man. J Clin Endocrinol 1967;27:481-90. 1' Santen RJ, Worgul T, Veldhuis J, et al. Randomized, controll...

1. Fishman JR, Merrill DC. A case of giant prostatic hyperplasia. Urology 1993;42:336-7. 2. Sarretta V, Morgia G, Fondacaro L, Curto G, Lo bianco A, Pirritano D, et al. Open prostatectomy for benign prostatic enlargement in southern Europe in the late 1990s: A contemporary series of 1800 interventions. Urology 2002;60:623-7. 3. Condie JD, Cutherell L, Mian A. Suprapubic prostatectomy for benign...

Long-term natural history studies are important in rare disease research. This study aimed to assess electrophysiological and fundus autofluorescence (FAF) progression rate 18 genetically confirmed Stargardt (STGD1) patients with a minimum follow-up of 10 years. Age at the first last exams, age onset, Snellen decimal visual acuity (VA), electroretinography (ERG), FAF images were evaluated. Pati...

The preparation of an extract from animal tissues containing an enzyme specific for the hydrolysis of &glucuronides was first described by Masamune (1). Oshima (2,3) later studied the distribution of this enzyme in the tissues of the dog and the ox and improved the method of preparation of active extracts. At the suggestion of Professor G. F. Marrian an investigation was undertaken to determine...

5

Endothelial and hematopoietic cells appear synchronously on the extra-embryonic membranes of amniotes in structures known as blood islands. This observation has led to the suggestion that these two ventral lineages share a common progenitor. Recently, we have shown in the zebrafish, Danio rerio, that a single cell in the ventral marginal zone of the early blastula can give rise to both endothel...