A system was developed to detect the self-replication of an RNA enzyme in real time. The enzyme is an RNA ligase that undergoes exponential amplification at a constant temperature and can be made to operate in a ligand-dependent manner. The real-time system is based on a fluorimetric readout that directly couples the ligation event to an increase in florescence signal that can be monitored usin...

The preparation of monodisperse nanoparticles with uniform size, shape and composition has been intensively pursed because of their scientific and technological interests [1-4]. The major advantage of monodisperse particles may be attributed to the uniform properties of individual particles, which makes the property of whole particles strictly controllable. They have been widely used in industr...

We introduce single-molecule spectroelectrochemistry (SMS-EC), a powerful new technique for studying electrochemical kinetics in highly heterogeneous systems. This technique uses fluorescence single-molecule spectroscopy to indirectly measure electrochemical kinetics one molecule at a time, offering for the first time the distribution of key electrochemical variables, such as the half-wave pote...

In this work, two Schiff base ligands Z2a and Z2b derived from 5-aminoisophthalic acid were synthesized their structures characterized by FTIR, 1H(13C) NMR mass spectrometries. The compounds investigated for chemosensor properties towards metal ions [Na+, K+, Al3+, Cr3+, Mn2+, Fe3+, Co2+, Ni2+, Cu2+, Zn2+, Cd2+, Hg2+ Pb2+] examined using colorimetric spectrophotometric methods (UV-Vis absorptio...

Africa from Marine Isotope Stages (MIS) 6-2 saw the crystallization of long-term evolutionary processes that culminated in our species’ anatomical form, behavioral florescence, and global dispersion. Over this *200 kyr period, Africa experienced environmental changes on a variety of spatiotemporal scales, from the long-term disappearance of whole deserts and forests to much higher frequency, lo...

"Collision tumor" is an uncommon phenomenon characterized by coexistence of two completely distinct and independent tumors at the same site. Collision tumors have been reported in different sites in the body; however, these are particularly uncommon in the pelvic cavity. A 70-year-old man, with prior history of urothelial and prostate cancer, presented with a large pelvic mass detected on imagi...

Submit Manuscript | http://medcraveonline.com Abbreviations: AIDS: Acquired Immune Deficiency Syndrome; BCBL: Body Cavity Based Lymphoma Cell Line; CSWS: Commercial Sex Workers; DNA: Deoxyribonucleic Acid; EIA: Enzyme Immune Assays; ELISA: Enzyme Linked Immunosorbent Assays; FSWS: Female Sex Workers; HBV: Hepatitis B Virus; HCV: Hepatitis C Virus; HHV-8: Human Herpes Virus Type 8; HIV: Human Im...

The integration of high charge carrier mobility and high luminescence in an organic semiconductor is challenging. However, there is need of such materials for organic light-emitting transistors and organic electrically pumped lasers. Here we show a novel organic semiconductor, 2,6-diphenylanthracene (DPA), which exhibits not only high emission with single crystal absolute florescence quantum yi...