Splenic lymphoma with circulating villous lymphocytes (SLVL) is an indolent B-cell neoplasm. Because of its rarity, a definitive diagnosis often becomes difficult. In this study we are going to discuss about two cases of SLVL. Despite being a variant of lymphoma peripheral lymphadenopathy is not found in such cases. Careful analysis of blood or bone marrow sample by flow cytometry may be helpfu...

Background: Contributing factors for improved survival of human adipocytes mesenchymal stem cells (h-AMSCs) cultured through hypoxia preconditioning, in example apoptosis inhibition involving BCL2 and HSP27 expression, trigger signal expression (VEGF), SCF OCT-4 CD44+ expression. The objective if this study was to explain the mechanism role hypoxic preconditioning op...

Nefropati diabetik adalah salah satu penyebab utama gagal ginjal dan kematian tertinggi diantara semua komplikasi diabetes mellitus. Anemia paling sering terjadi pada pasien DM, khususnya jika disertai dengan nefropati atau gangguan renal. Tujuan penelitian ini untuk melihat Profil Pada Pasien Diabetes Mellitus Penderita Diabetik. Metode yang digunakan yaitu Deskriptif Observasional. Penelitian...

Background: Regulatory T Cells (Treg) are the subgroups of lymphocytes that control inflammatory responses and regulate homeostasis processes through cellular contact secretion soluble agents. We investigated frequency Treg in peripheral blood sulfur mustard exposed patients with CD4, CD25, CD127, FOXP3, CD45RA markers, compared healthy individuals correlation between these cells long-term pulm...

Lymphoid malignancies represent a wide variety of disease entities characterized by malignant proliferation of lymphoid cells which have distinct clinical features, cellular morphology, immunophenotype, cytogenetic changes and histologic features. CD40 is a member of the tumor necrosis factor receptor super-family. It was first identified and characterized in B cell, signaling through the CD40 ...

Morphological microscopic examinations of nucleated cells in body fluid (BF) samples are performed to screen malignancy. However, the morphological differentiation is time-consuming and labor-intensive. This study aimed to develop a new flowcytometry-based gating analysis mode "XN-BF gating algorithm" to detect malignant cells using an automated hematology analyzer, Sysmex XN-1000. XN-BF mode w...

Background: After achieving morphological remission, existence of few number of leukemic cells in the patient’s blood represents the minimal residual disease (MRD) and its monitoring helps in evaluating early treatment response and future relapse. Patients and methods: Eighty seven newly diagnosed (B-ALL) cases were enrolled in the present study in the time period from October 2013 to October 2...

We analyzed genetic changes in condylomas (four cases), vulvar intraepithelial neoplasia I-III (VIN I-III, eleven cases), and primary vulvar squamous cell carcinomas (VSCC, ten cases) by high-resolution comparative genomic hybridization (HR-CGH) and flowcytometry. All samples were also human papilloma virus (HPV)-genotyped. Gain of chromosome 1, the aberration most often seen in VIN III (67%), ...