The responses of cerebral (pial) arterioles to increased venous pressure were examined in anesthetized cats equipped with cranial windows for the observation of the cerebral microcirculation. Increased venous pressure was induced by occlusion of the superior vena cava. Intracranial pressure was kept constant. Increased venous pressure when the window was filled with stationary cerebrospinal flu...

Highly organized mesoporous silica monoliths were reproducibly prepared by nanocasting mixtures of fluorinated nonionic surfactants and micelles of two hydrocarbon block copolymers. It is the special feature of this fluorocarbon/hydrocarbon template mixture that they form not mixed micelles but individual micelles instead. By careful analysis of the pore architectures by gas sorption measuremen...

The chemical modification of polystyrene through the deposition of a beam of polyatomic fluorocarbon ions (C3F5 and CF3) at experimental fluences is studied using classical molecular dynamics simulations with many-body empirical potentials. To facilitate these simulations, a new C-H-F potential is developed on the basis of the second-generation reactive empirical bond-order potential for hydroc...

Inhalation of fluorocarbon polymers can cause pulmonary toxicity. Although multiple cases of lung injury have been reported, cellular characterization of the associated alveolitis occurring acutely after inhalation is limited. We report the case of a previously healthy woman who presented at our Emergency Department with an acute pneumonitis following inhalation of a fluorocarbon polymer-based ...

This study is the first attempt at extending the Interfacial Lift-off CHF Model to subcooled flow boiling conditions. A new CHF database was generated for FC-72 from ground tests as well as from microgravity tests that were performed in parabolic flight trajectory. These tests also included high-speed video imaging and analysis of the liquid–vapor interface during the CHF transient. Both the CH...

A novel perfluorinated magnesium phthalocyanine (MgPcF64) was synthesized and employed to probe nanodomains in hydrophobically modified, amphiphilic cationic polyelectrolytes bearing alkyl and/or fluoroalkyl side chains. MgPcF64 was found to be solubilized exclusively in the aqueous solutions of the fluorocarbon modified polycations, occupying the perfluorinated nanocompartments provided, while...

Biomedical investigations with small animals using 0.5-T and 7-T MRI scanners adjusted on the Larmor frequencies of different nuclei 1H, 2H, 11B, 13C, 19F, 23Na, 31P, 35Cl are described. Experiments on registration of signals 19F from the fluorocarbons injected in laboratory animals are discussed. They give presentation on the application of fluorocarbon compounds as blood substitutes and contr...

We developed new benzofurazan (NBD) labeled probes for fluorocarbon surfactant systems. The fluorescence behavior depended on the solubilization site of the fluorescent probes in the surfactant aggregates. The NBD-labeled probes suffered virtually complete reduction in the presence of Na2S2O4 owing to the solubilization at the surface of 2-hydroxy-1,1,2,3,3-pentahydroperfluoroundecyldiethylammo...

Drops of water-in-fluorocarbon emulsions have great potential for compartmentalizing both in vitro and in vivo biological systems; however, surfactants to stabilize such emulsions are scarce. Here we present a novel class of fluorosurfactants that we synthesize by coupling oligomeric perfluorinated polyethers (PFPE) with polyethyleneglycol (PEG). We demonstrate that these block copolymer surfac...

The responses of cerebral (pial) arterioles to increased venous pressure were examined in anesthetized cats equipped with cranial windows for the observation of the cerebral microcirculation. Increased venous pressure was induced by occlusion of the superior vena cava. Intracranial pressure was kept constant. Increased venous pressure when the window was filled with stationary cerebrospinal flu...