To identify novel genes involved in early mammalian folliculogenesis, we used the Unigene collection of mouse cDNA libraries to identify unique expressed sequence tags in a newborn mouse ovary cDNA library. Nobox (newborn ovary homeobox-encoding gene) was one of several genes identified by in silico (electronic database) subtraction. We cloned the mouse Nobox cDNA and characterized its genomic ...

Ovarian folliculogenesis is a dynamic process characterized by a marked proliferation and differentiation of the somatic cell components of the follicle. The developing follicle provides the optimal environment for the maturation of the oocyte in readiness for its subsequent fertilization after ovulation. The primary regulators of folliculogenesis are the gonadotrophins, which regulate ovarian ...

Objective: Exercise is a risk factor for infertility in women. However, research on the effects of different intensities exercise folliculogenesis has not yielded clear results. This study was conducted to analyze differences intensity mice. Methods: Nineteen female BALB/c mice (age, 3–4 months; weight, 13–25 g) were randomly divided into four groups: control, mild exercise, moderate and high-i...