To assess the effects of extreme exercise on lung function we measured maximal expiratory flow volume (MEFV) curves in fifteen runners (mean age, 35.3 years; range, 26-46) before and after an 80.6 to 100 km (50-62.2 mile) road race. Mean running time for 80.6 km was 7 hr, 42 min. Post-race testing showed significant decreases of 12.4 percent in forced vital capacity (FVC), 9.5 percent in forced...

Expiratory flow limitation (EFL), which promotes dynamic hyperinflation and increased work of breathing, often occurs in chronic obstructive pulmonary disease (COPD). The purpose of this study was to assess the effect of bronchodilators on EFL and end-expiratory lung volume in patients with moderate-to-severe COPD. EFL was assessed by applying negative expiratory pressure (NEP) at the mouth dur...

OBJECTIVE Cardiovascular, respiratory and musculoskeletal system disorders which may affect the functional exercise capacity are common in obese patients. We aimed to investigate the functional exercise capacity and its relationship with functional pulmonary capacity in obese children. METHODS A total of 74 obese and 36 healthy children as a control group were enrolled in the study. Pulmonary...

OBJECTIVE(S) As not only few evidences but also contradictory results exist with regard to the effects of resistance training (RT) and resistance plus endurance training (ERT) on respiratory system, so the purpose of this research was therefore to study single and concurrent effects of endurance and resistance training on pulmonary function. MATERIALS AND METHODS Thirty seven volunteer health...

Dietary antioxidants may protect lung tissue against reactive oxygen species-induced injury, adverse respiratory effects and reduced pulmonary function. Genetic variability in antioxidant enzymes also determines response to oxidative stress in the lung. The current authors evaluated whether lung function levels are associated with dietary intake of antioxidants and the glutathione S-transferase...

c-reactive protein (crp) is an acute-phase protein synthesized predominantly by the hepatocytes in response to tissue damage or inflammation. levels of acute-phase proteins rise rapidly, during infection and after injury. we take up the study to correlate serum crp levels with other important predictive markers of outcome in copd. patient with stable copd (no exacerbation in the last two months...

OBJECTIVES The purpose of this study was to quantify the time-varying changes in pulmonary function with exposure to prolonged sitting. METHODS Twenty-one healthy volunteers were recruited. The pulmonary function of all participants was measured three times in order to assess changes over time; pulmonary function was measured before sitting, after participants had been seated for 1 hour, and ...

introduction: renal failure affects the mechanical and the ventilatory function of the lungs. a few studies have evaluated the ventilatory and pulmonary function in dialysis patients. the present study aimed to compare pulmonary function test (pft) results in patients undergoing hemodialysis (hd) and peritoneal dialysis (pd). materials and methods: we conducted a cross-sectional study on 50  pa...

OBJECTIVE In clinical practice, spirometry is a extremely useful test that requires strict quality control, an appropriate strategy for interpretation, and reliable reference values. The aim of this study was to report spirometric reference values for 5 cities in Latin America. PATIENTS AND METHODS From data for 5315 subjects who had undergone spirometry in the PLATINO study in Caracas, Mexic...

Analysis of airflow in the terminal portion of the maximal expiratory flow volume curve has been suggested as a useful test for the early diagnosis of chronic airways obstruction. Whether such an analysis can identify early disease, and whether any subsequent action can prevent the progress of chronic airways obstruction, is unknown and will require prospective studies. As a precursor of such a...