OBJECTIVE To define the bronchodilator response (BDR) cutoff point that best identified asthma to determine the frequency of abnormal spirometry results across severity. STUDY DESIGN Controller naïve children were evaluated with clinical criteria alone to establish a diagnosis of asthma and severity classification, then compared with the BDR, which was calculated as the percent change from th...

During a five year observation period, declines of forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) were investigated in 200 subjects with diabetes mellitus (DM), 126 subjects who developed DM during that period and 9,051 nondiabetic subjects. After statistical adjustment for age, sex, height, and tobacco consumption we found that the subjects who developed DM durin...

The forced expiratory manoeuvre was first described by Tiffeneau and Pinelli working in Paris (France), in December 1947, who proposed measurement of the "pulmonary capacity usable on exercise" (capacité pulmonaire utilisable à l'effort) (CPUE), the maximal volume expelled in one second after a deep inspiration. It was intended to replace the measurement of the maximum breathing capacity, a dif...

We investigated ventilation inhomogeneity during provocation with inhaled histamine in 20 asymptomatic nonsmoking subjects. We used N2 multiple-breath washout (MBW) to derive parameters Scond and Sacin as a measurement of ventilation inhomogeneity in conductive and acinar zones of the lungs, respectively. A 20% decrease of forced expiratory volume in 1 s (FEV1) was used to distinguish responder...

The association between ambient temperature and lung function in children with asthma is still uncertain. A panel of 270 children (aged 7-12 years) with asthma was recruited from six Australian cities. They performed three successive forced expiratory manoeuvres twice daily for 4 weeks. The highest peak expiratory flow rate (PEF) and forced expiratory volume in 1 s (FEV1) were stored for each s...

BACKGROUND Pulmonary function tests (PFTs) are used in assessing physiological to clinical status of the respiratory system, which is expressed as a percentage of predicted values. Predicted PFTs values are varies in different ethnics. Predicted PFTs values were studied in a sample of Iranian children. MATERIALS AND METHODS Prediction equations for PFTs were derived from urban children in the...

OBJECTIVE To predict pulmonary function test values in children. METHODS This cross-sectional study was carried out at Nishtar Medical College, Multan, Pakistan, from August 2014 to March 2015, and comprised school-going children aged 5-14 years. After noting their gender, age, height and weight, the pulmonary function test measures, force vital capacity, forced expiratory volume in 1 second ...

BACKGROUND The aims of this study were to verify the feasibility of respiratory function tests and to assess their validity in the diagnosis of respiratory disorders in young children. METHODS We performed spirometry and collected information on health and parents' lifestyle on a sample of 960 children aged 3-6. RESULTS The cooperation rate was 95.3%. Among the valid tests, 3 or more accept...

The aim of this study is to assess the influence of the negative expiratory pressure (NEP) technique on the performance of maximal expiratory manoeuvre in elderly patients. Firstly, the authors studied how NEP (at 5 and 10 cmH2O, NEP5 and NEP10) influences forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) in 60 young healthy volunteers, in order to assess the fluctua...

The use of noseclips for open-circuit spirometry is sporadic, despite guidelines encouraging their use. The authors aimed to evaluate whether noseclips significantly affected measurements of forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) in children attending a tertiary, paediatric respiratory centre. Children attending the asthma and cystic fibrosis (CF) clinics ...