Background: In dental practice concomitant exposure to formaldehyde and glutaraldehyde is a common occurrence. The objective of the study is to evaluate the incidence of occupational contact dermatitis to formaldehyde and glutaraldehyde in dental professionals and the manifestation of co-reactivity. Methods and Results: This study involved 78 participants (30 dental professionals and 48 referen...

An NADand GSH-dependent formaldehyde dehydrogenase (formaldehyde: NAD* oxidoreductase, EC 1.2.I.Z) was purified from rat and human liver, and the properties of these enzymes were compared. The GSH requirement of the enzyme obtained from both species could not be replaced by dithiothreitol, CoA or cysteine, and NADP could not substitute for NAD. The pH optimum, and the Km of formaldehyde and NAD...

in this study, the particleboard was made with rice husk and urea formaldehyde resin of 7, 8, 9 and 10 percent (based on dry weight of rice husk). to improve mechanism of bondability a definite amount of isocyanate resin is introduced to replace the same amount of urea formaldehyde resin. the effect of urea formaldehyde resin and diisocyanate content on bondability was evaluated by studying the...

Formaldehyde is an intermediate formed during the metabolism of methanol or other methylated compounds. Many Gram-negative bacteria generate formaldehyde from methanol via a periplasmic pyrroloquinoline quinone (PQQ)-dependent dehydrogenase in which the alpha subunit of an alpha(2)beta(2) tetramer has catalytic activity. The genome of the facultative formaldehyde-oxidizing bacterium Rhodobacter...

BACKGROUND The common causes of textile dermatitis are formaldehyde resins and disperse dyes. There are various methods to detect the presence of formaldehyde in clothing. AIM To detect the presence of formaldehyde in various types of textiles by the chromotropic acid method and to assess the effect of washing on the formaldehyde content. METHODS Twenty randomly selected textiles from a loc...

BACKGROUND Formaldehyde is used in medicine and industry, and it is known to have detrimental effects on various systems including the nervous system, by increasing oxidative stress. However, data are scarce related to substances that can protect against the neurotoxicity induced by formaldehyde. Therefore, this study was designed to assess the protective effects of selenium against the toxic e...

BACKGROUND There is current interest in understanding the molecular mechanisms of tumor-induced bone pain. Accumulated evidence shows that endogenous formaldehyde concentrations are elevated in the blood or urine of patients with breast, prostate or bladder cancer. These cancers are frequently associated with cancer pain especially after bone metastasis. It is well known that transient receptor...

The ADH2 gene codes for the Arabidopsis glutathione-dependent formaldehyde dehydrogenase (FALDH), an enzyme involved in formaldehyde metabolism in eukaryotes. In the present work, we have investigated the potential role of FALDH in detoxification of exogenous formaldehyde. We have generated a yeast (Saccharomyces cerevisiae) mutant strain (sfa1Delta) by in vivo deletion of the SFA1 gene that co...

Background The South Korean criteria for occupational diseases were amended in July 2013. These criteria included formaldehyde as a newly defined occupational carcinogen, based on cases of "leukemia or nasopharyngeal cancer caused by formaldehyde exposure". This inclusion was based on the Internal Agency for Research on Cancer classification, which classified formaldehyde as definite human carc...

Formaldehyde is a prevalent environmental toxin and a key intermediate in single carbon metabolism. The ability to monitor formaldehyde concentration is, therefore, of interest for both environmental monitoring and for metabolic engineering of native and synthetic methylotrophs, but current methods suffer from low sensitivity, complex workflows, or require expensive analytical equipment. Here w...