نتایج جستجو برای: formation damage

تعداد نتایج: 739620  

Journal: :Cell 2007
Sonja Schaetzlein N. R. Kodandaramireddy Zhenyu Ju Andre Lechel Anna Stepczynska Dana R. Lilli Alan B. Clark Cornelia Rudolph Florian Kuhnel Kaichun Wei Brigitte Schlegelberger Peter Schirmacher Thomas A. Kunkel Roger A. Greenberg Winfried Edelmann K. Lenhard Rudolph

Exonuclease-1 (EXO1) mediates checkpoint induction in response to telomere dysfunction in yeast, but it is unknown whether EXO1 has similar functions in mammalian cells. Here we show that deletion of the nuclease domain of Exo1 reduces accumulation of DNA damage and DNA damage signal induction in telomere-dysfunctional mice. Exo1 deletion improved organ maintenance and lifespan of telomere-dysf...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه صنعتی اصفهان - دانشکده فیزیک 1390

in this thesis, barium ferrite nano particles were prepared by sol-gel method. their structural and magnetic properties of samples have been investigated using thermo gravimetric analysis (tg-dta), x-ray powder diffractometer (xrd), fourier transform infrared (ftir), scanning electron microscopy (sem), field emission scanning electron microscopy (fesem), ac susceptometer, vibrating sample magne...

2015
Askar Yimit Michael Riffle Grant W Brown

DNA damage response pathways are crucial for protecting genome stability in all eukaryotes. Saccharomyces cerevisiae Dna2 has both helicase and nuclease activities that are essential for Okazaki fragment maturation, and Dna2 is involved in long-range DNA end resection at double-strand breaks. Dna2 forms nuclear foci in response to DNA replication stress and to double-strand breaks. We find that...

2016
Elisa Romanelli Doron Merkler Aleksandra Mezydlo Marie-Theres Weil Martin S. Weber Ivana Nikić Stephanie Potz Edgar Meinl Florian E. H. Matznick Mario Kreutzfeldt Alexander Ghanem Karl-Klaus Conzelmann Imke Metz Wolfgang Brück Matthew Routh Mikael Simons Derron Bishop Thomas Misgeld Martin Kerschensteiner

Oligodendrocyte damage is a central event in the pathogenesis of the common neuroinflammatory condition, multiple sclerosis (MS). Where and how oligodendrocyte damage is initiated in MS is not completely understood. Here, we use a combination of light and electron microscopy techniques to provide a dynamic and highly resolved view of oligodendrocyte damage in neuroinflammatory lesions. We show ...

Water flooding is one of the most influential methods for pressure maintenance and enhanced oil recovery. However, water flooding is likely to develop the formation of oilfield scale. Scale formation in reservoirs, due to the mixing of injection water and formation water, could cause formation damage and production limit. Therefore, it is necessary to simulate the compatibility of brine and inj...

Journal: :Journal of the Japanese Association for Petroleum Technology 2006

Journal: :Journal of Petroleum Exploration and Production Technology 2020

Journal: :Journal of Earth Energy Science, Engineering, and Technology 2020

Journal: :Biomedical Journal of Scientific & Technical Research 2018

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