The use of pharmacoeconomic (PE) evaluations for formulary decision-making has become increasingly common. When a new drug is being considered for inclusion on a formulary, the drug is compared with other available alternatives with respect to efficacy and effectiveness, safety, and cost. The 5-hydroxytryptamine agonists, also known as triptans, are being used to a greater extent as first-line ...

BACKGROUND The Academy of Managed Care Pharmacy (AMCP) Format for Formulary Submissions, a template for health plans to use in developing formulary submission guidelines, has been widely adopted since its initial release in 2000. Many health plans request a dossier (a standardized set of clinical and economic evidence prepared by pharmaceutical manufacturers) to provide information for consider...

The use of fluoroquinolones has been linked to increasing bacterial resistance and infection and/or colonization with already resistant pathogens both as a risk factor and based on volume of use. Changes in individual fluoroquinolones used in an institution may also be related to these clinical problems. Interrupted time series analysis, which allows for assessment of the associations of an out...

BACKGROUND Previous studies have suggested that prescribing formularies may promote rational prescribing. The range of drugs prescribed may be one aspect of rational prescribing. AIM To determine whether the introduction of prescribing formularies helps general practitioners (GPs) to prescribe from a narrower range of non-steroidal anti-inflammatory drugs (NSAIDs). METHOD General practices ...

OBJECTIVES This paper investigates the pricing strategy (perfect flat pricing, perfect monotonic pricing, intermediate) used for multiple dosage medications listed in the Ontario Drug Benefit Formulary. METHODS All multiple dosage solid medications containing a single active ingredient newly listed in the Ontario Drug Benefit Formulary between 1996 and 2005 were identified. The relationship b...

made each five years. Subsequent changes and corrections are printed in the Journal of the American Pharmaceutical Association. XVhenever necessary, supplements are issued. The criterion for admission of a drug to the National Formulary is its use, whereas criteria for the United States Pharmacopeia are indispensibility, uniqueness, and proved worth. The contents of the two books are mutually e...

PURPOSE Insurance plans periodically change their formularies to enhance medical efficacy and cost savings. Patients face challenges when formulary changes affect their treatment. This study assessed the impact of insurance-driven medication changes on primary care patients and examined implications for patient care. METHODS We mailed questionnaires to a cross-sectional random sample of 1200 ...

IMPORTANCE Without third-party insurance, access to marketed drugs is limited to those who can afford to pay. We examined this phenomenon in the context of anticoagulation for patients with nonvalvular atrial fibrillation (NVAF). OBJECTIVE To determine whether, among older Ontarians receiving anticoagulation for NVAF, patients of higher socioeconomic status (SES) were more likely to switch fr...

the present study was performed to explore the matrix property of ficus glomerata fruit mucilage for making transdermal patches. the mucilage was evaluated for its physicochemical properties. various transdermal patches of indomethacin were prepared by solvent evaporation technique using different proportions of f. glomerata fruit mucilage. the compatibility studies between indomethacin and f. ...