Brain tissue being rich in polyunsaturated fatty acids, is very susceptible to lipid peroxidation. Iron is well known to be an important initiator of free radical oxidations. We propose that the principal route to iron-mediated lipid peroxidations is via iron-oxygen complexes rather than the reaction of iron with hydrogen peroxide, the Fenton reaction. To test this hypothesis, we enriched leuke...

A direct approach for producing methanol from methane in a three-step, liquid phase process is reported. In the first step, methane is reacted with SO3 to form methanesulfonic acid (MSA) at 75 8C using a free-radical initiator and MSA as the solvent. Urea-H2O2 in combination with RhCl3 is found to be the most effective initiator (57% conversion of SO3; 7.2% conversion of CH4). MSA is then oxidi...

A mean-field kinetic model was developed to describe a diffusion-controlled bulk cross-linking photopolymerization. This model incorporates all the physical transport limitations that directly or indirectly affect polymerization parameters and rate constants in such reactions. Events such as the continuous decrease in initiator efficiency and the presence of a temporary excess free volume were ...

The direct addition reaction of chloroform to cyclopropenes under triethylborane-mediated radical reaction conditions to provide trichloromethylcyclopropanes has been developed. In contrast, using dimethylzinc as a radical initiator led to the formation of unconjugated esters via a domino sequence involving the addition of the trichloromethyl radical, rearrangement and ring-opening reactions.

Radical trifluoromethylation of aryl N,N-dimethyl hydrazones using TBAI as an initiator and Togni's reagent as a trifluoromethyl radical source is described. Cascades proceed via electron-catalysis; this approach is generally more applicable to hydrazone perfluoroalkylation using perfluoroalkyl iodides as the radical precursors in combination with a base under visible-light initiation.

reactions of free radicals and reactive oxygen species (ros) with biological molecules in vivo play an important physiological role in many diseases. 2,2-diphenyl-1-picrylhydrazyl (dpph) is a stable free radical and often used as a routine reagent to evaluate the antioxidant capacity of an antioxidant. this study was undertaken to investigate the free radical-scavenging and antioxidant activiti...

Objective(s): The main aim of current research was to develop a novel magnetically responsive hydrogel by radical polymerization of carboxymethyl cellulose (CMC) on acryl amide (Am) using N,N'-methylene bis acrylamide  (MBA)  as a crosslinking agent, potassium persulfate (KPS) as a free radical initiator, and  magnetic montmorillonite ( mMT)  nanoclay as nano-...

Abstract The unique properties of fluorine-containing organic compounds make fluorine substitution attractive for the development pharmaceuticals and various specialty materials, which have inspired evolution diverse C-F bond activation techniques. Although many advances been made in functionalizations activated bonds utilizing transition metal complexes, there are fewer approaches available no...