think of her as hostess to her brother, Roger Fry, and at ease with Paris and Bloomsbury of the 20s, or as companion to her father, Sir Edward Fry, ten years earlier in the world of international diplomacy. Mental health was a marginal interest to her. But it should be gratefully remembered that in 1908 she was engaged with Lady Adrian's mother in the 'feeble-minded agitation' which led to the ...

My research focuses on studying the software maintenance process, especially as it relates to humans, in an effort to reduce the overall cost of maintaining large systems. I feel that this problem is of paramount importance as maintenance accounts for the great majority of the cost associated with the software lifecycle. It has remained largely a human-centric, manual process despite increasing...

5. Gaia V, Fry NK, Afshar B, Luck PC, Meugnier H, Etienne J, et al. Consensus sequence-based scheme for epidemiological typing of clinical and environmental isolates of Legionella pneumophila. J Clin Microbiol. 2005;43:2047–52. 6. Ratzow S, Gaia V, Helbig JH, Fry NK, Luck PC. Addition of neuA, the gene encoding N-acylneuraminate cytidylyl transferase, increases the discriminatory ability of the...

An experimental model for immersion challenge of rainbow trout fry (Oncorhynchus mykiss) with Flavobacterium psychrophilum, the causative agent of rainbow trout fry syndrome and bacterial cold water disease was established in the present study. Although injection-based infection models are reliable and produce high levels of mortality attempts to establish a reproducible immersion model have be...

This paper discusses the mechanics and implications of municipal concessions in the Philippines which govern the use of municipal waters for fish corrals, oyster culture beds and gathering of milkfish fry. These concessions or territorial use rights are awarded annually by the resource owner (the municipality) to the highest bidder. In the case of milkfish fry gathering, the concessionaire assu...

This is the first study analysing individual differences in shyness–boldness and behavioural asymmetries in young zebrafish larvae (fry, 7 days post-fertilisation). Individual differences were more stable in tests with predator model (crude image of a fish face) than with an arbitrary novel stimulus (vertical black stripe). Principal component analysis revealed a dimension of ‘shyness’ that inv...

We have tested whether immunity can be transferred from a mother fish to its fry. Rainbow trout mother fish were inoculated against infectious haematopoietic necrosis virus (IHNV) by intraperitoneal injection of a fragment of the IHNV glycoprotein spanning amino acids 31 to 310. This protein fragment was obtained by isolating the specific cDNA from Japanese IHNV strain HV7601 and expressing it ...

Artificial light at night (ALAN) is gaining recognition as having an important anthropogenic impact on the environment, yet the behavioural and physiological impacts of this stressor are largely unknown. This dearth of information is particularly true for freshwater ecosystems, which are already heavily impacted by anthropogenic pressures. Atlantic salmon (Salmo salar L.) is a species of conser...

The in vivo antiviral effect of 5-ethynyl-1-b-D-ribofuranosylimidazole-carboxamide (EICAR) was evaluated in coho salmon and rainbow trout fry, experimentally infected with infectious pancreatic necrosis virus (IPNV). Treatment consisted of a daily bath of 2 h in 0.4 mg ml or 0.8 mg ml of EICAR, for approximately 20 days. The behavior of the fish was studied for 45 days post-infection. The survi...

Persistent organic pollutants (POPs) are resistant to environmental degradation and can cause multitude of health problems. Cytochrome P450 1A (Cyp1a) is often up-regulated by POPs through the activation of aryl hydrocarbon receptor (AhR) pathway and is thus usually used as a biomarker for xenobiotics exposure. To develop a convenient in vivo tool to monitor xenobiotic contamination in the wate...