Dimers of metal nanospheres are well-known for their characteristic anisotropic optical response. Here, we demonstrate in single-particle SERS experiments that individual gold trimers and 3D superstructures exhibit a polarization-independent SERS response. This optical behavior of single particle clusters provides constant SERS signals, independent of the mutual orientation of the incident lase...

The reduced graphene oxide/silver nanotriangle (rGO/AgNT) composite sol was prepared by the reduction of silver ions with sodium borohydride in the presence of H2O2 and sodium citrate. In the nanosol substrate, the molecular probe of acridine red (AR) exhibited a weak surface-enhanced Raman scattering (SERS) peak at 1506 cm(-1) due to its interaction with the rGO of rGO/AgNT. Upon addition of d...

Simultaneous detection of multiple molecular targets can greatly facilitate early diagnosis and drug discovery. Encoding micron-sized beads with optically active tags is one of the most popular methods to achieve multiplexing. Noble metal nanoparticle labels for optical detection by surface-enhanced Raman spectroscopy (SERS) exhibit narrow bandwidths, high photostability and intense Raman signa...

One of the current limitations surrounding surface-enhanced Raman scattering (SERS) is the perceived lack of reproducibility. SERS is indeed challenging, and for analyte detection, it is vital that the analyte interacts with the metal surface. However, as this is analyte dependent, there is not a single set of SERS conditions that are universal. This means that experimental optimisation for opt...

Abstract Herein, we demonstrate the effectiveness of surface-enhanced Raman scattering (SERS) to detect trace concentration potentially harmful imidacloprid pesticide. To achieve this ultimate objective, a rapid and highly effective methodology for fabrication active stable porous silicon (PSi) plated palladium nanoparticles (PdNPs) SERS substrates by an electrochemical anodization immersion pl...

A microfluidic setup which enables on-line monitoring of residues of malachite green (MG) using surface-enhanced Raman scattering (SERS) is reported. The SERS active substrate was prepared via laser induced synthesis of silver or gold nanoparticles spot on the bottom of a 200 μm inner dimension glass capillary, by focusing the laser beam during a continuous flow of a mixture of silver nitrate o...

This paper reports the possibility of monitoring the sweetener content in the leaves of Stevia Rebaudiana and root extract of Ginseng using FT-IR, micro-Raman and SERS techniques. Fingerprint analysis is a direct, fast, nondestructive and effective method to discriminate and identify different species. Ginseng root contains ginsengoside saponin about 4% and other active compounds such as D-gluc...

Simultaneous measurement of surface-enhanced Raman scattering (SERS) and localized surface plasmon resonance (LSPR) in nanoparticle dimers presents outstanding opportunities in molecular identification and in the elucidation of physical properties, such as the size, distance, and deformation of target species. SERS-LSPR instrumentation exists and has been used under limited conditions, but the ...

Surface-enhanced hyper-Raman scattering (SEHRS) and surface-enhanced Raman scattering (SERS) of para-mercaptobenzoic acid (pMBA) were studied with an excitation wavelength of 1064 nm, using different silver nanostructures as substrates for both SEHRS and SERS. The spectra acquired for different pH values between pH 2 and pH 12 were compared with SERS data obtained from the identical samples at ...

This review covers from the basic principles of Raman spectroscopy to the advanced technique of surface enhanced Raman Scattering (SERS) spectroscopy. After briefly going through the description of Raman and introduction of the development of SERS, the article will focus on the “hotspot” of the current research work on SERS – single molecule spectroscopy. We will see later that “hotspot” is als...