Hiatal hernia (HH) is associated with gastro-oesophageal reflux (GOR) and/or GOR disease and may contribute to idiopathic pulmonary fibrosis (IPF). We hypothesised that HH evaluated by computed tomography is more common in IPF than in asthma or chronic obstructive pulmonary disease (COPD), and correlates with abnormal GOR measured by pH probe testing. Rates of HH were compared in three cohorts,...

SIR—We read with interest the article by Clayton et al. on tracheal pH monitoring and aspiration in acute stroke [1] and agree with their suggestion that research into this area is much needed. We have been concerned about the risk of aspiration in patients with dysphagic stroke who are fed by percutaneous endoscopic gastrostomy (PEG) tube. The median survival of PEG-fed stroke patients is 10 m...

This article proposed a simple self cascode RGC amplifier configuration to increase the gain and bandwidth. The cascode amplifier eliminates the miller capacitance between input and output and facilitates high gain, high input and output impedance with high bandwidth. However, the cascode amplifier requires relatively high supply voltage for proper operation and it decreases the output voltage ...

Fast pulse polarity switching is proposed and demonstrated to enhance processing gain in a comb-based radio-frequency photonic phase filter. The polarity switching scheme overcomes previous limits on time bandwidth product and processing gain based on the number of optical frequency comb lines. In an experiment with broadband jamming noise, the peak signal-to-noise ratio of compressed RF output...

We have modified and improved the GOR algorithm for the protein secondary structure prediction by using the evolutionary information provided by multiple sequence alignments, adding triplet statistics, and optimizing various parameters. We have expanded the database used to include the 513 non-redundant domains collected recently by Cuff and Barton (Proteins 1999;34:508-519; Proteins 2000;40:50...

In this work, a non-isolated high step up DC-DC converter using coupled inductor and voltage multiplier cell is proposed. The proposed converter conversion ratio is efficiently extended by using a coupled inductor. An interleaved configuration of two diode-capacitor cells is applied to step up the voltage conversion ratio and decrease the voltage stress across the switches. Also, in the suggest...

In their in-depth review of chronic cough and gastro-oesophageal reflux (GOR), Fontana and Pistolesi suggest that proton pump inhibitors are the most effective treatment for GOR related cough. However, most studies evaluating the efficacy of proton pump inhibitors are not placebo controlled and do not use objective markers of cough severity to assess treatment responses. We are aware of two dou...

A novel two-switch high-step-up isolated converter with voltage lift is proposed in this paper. The proposed isolated converter utilizes a transformer with low turn ratio to achieve high step-up gain. The secondary winding charges two boosting capacitors in parallel as switches during the switch-on period, and two boosting capacitors are discharged in series during switch-off period. Thus, the ...

Between 1984 and 1994, 10 neurologically normal children between 2 and 24 months were diagnosed as having gastric volvulus with associated gastro-oesophageal reflux (GOR). The common features at presentation were episodic colicky abdominal pain, non-bilious vomiting, upper abdominal distension, haematemesis, and failure to thrive. Anterior gastropexy and conservative management of GOR was curat...