This paper examines the refereeing procedures at the scientific weekly Nature during and after World War II. In 1939 former editorial assistants L. J. F. Brimble and A. J. V. Gale assumed a joint editorship of Nature. The Brimble–Gale era is now most famous for the editors’ unsystematic approach to external refereeing. Although Brimble and Gale did sometimes consult external referees, papers su...

Our input is a bipartite graph G = (R ∪ H,E) where each vertex in R ∪ H has a preference list strictly ranking its neighbors. The vertices in R (similarly, in H) are called residents (resp., hospitals): each resident seeks to be matched to a hospital while each hospital h seeks cap(h) ≥ 1 many residents to be matched to it. The Gale-Shapley algorithm computes a stable matching in G in linear ti...

We report the identification of the allelochemical 3-(1-oxo-3-phenylpropyl)-1,1,5-trimethylcyclo-hexane-2,4,6-trione, known as myrigalone A, from the fruits and leaves of Myrica gale. The structure of the compound was confirmed by high-resolution techniques (UV, MS and NMR analysis). The compound is phytotoxic towards classical plant species used for allelochemical assays and also against Fallo...

The acetylene reduction assay was used to measure nonsymbiotic and symbiotic nitrogen fixation in a weakly minerotrophic peatland throughout the ice-free season. Nonsymbiotic nitrogen fixation was found in surface materials and subsurface peat. In surface materials, nitrogenase activity measured in the field contributed about 0.6 kg N ha-' yr-', was closely associated with Sphagnum, but was not...

UDP-galactose 4'-epimerase (GALE) catalyzes the interconversion of UDP-galactose and UDP-glucose, an important step in galactose catabolism. Type III galactosemia, an inherited metabolic disease, is associated with mutations in human GALE. The V94M mutation has been associated with a very severe form of type III galactosemia. While a variety of structural and biochemical studies have been repor...

Richard Gale’s slender monograph is a sometimes insightful, sometimes enervating and always personal reckoning with John Dewey’s philosophy. Gale’s basic thesis is that Dewey is a unificationist malgré lui, that despite being committed to empiricism and pluralism his pragmatism remains profoundly metaphysical in a non-naturalistic sense. This claim is hardly new or surprising. Thinkers as diver...

Lying in order to manipulate the Gale-Shapley matching algorithm has been studied by Dubins and Freedman (1981) and by Gale and Sotomayor (1985), and was shown to be generally more appealing to the proposed-to side (denoted as the women in Gale and Shapley’s seminal paper (1962)) than to the proposing side (denoted as men there). It can also be shown that in the case of lying women, for every w...

The Gale-Hoffman lemma characterizes feasible external flow (supply, demand) in a directed, capacitated network in terms of a number of linear inequalities. These inequalities are generated by considering all node subsets and requiring that the external flow associated with each subset be less or equal to the total capacity of the arcs exiting :from it. For a particularly appealing statement of...

Epimerase deficiency galactosemia is an autosomal recessive disorder that results from partial impairment of UDP-galactose 4'-epimerase (GALE), the third enzyme in the Leloir pathway of galactose metabolism. Clinical severity of epimerase deficiency ranges from potentially lethal to apparently benign, likely reflecting the extent of GALE enzyme impairment, among other factors. We report here a ...

We previously reported that mutation of galE in Porphyromonas gingivalis has pleiotropic effects, including a truncated lipopolysaccharide (LPS) O-antigen and deglycosylation of the outer membrane protein OMP85 homolog. In the present study, further analysis of the galE mutant revealed that it produced little or no outer membrane vesicles (OMVs). Using three mouse antisera raised against whole ...