objective(s): angiotensin ⅱ type 1 receptor blockers (arbs) represent one of the widely used antihypertensive agents. in addition to anti-hypertension effect, some arbs also show other molecular effects such as activating peroxisome proliferator-activated receptor-γ and so on. here we studied the effects of telmisartan on the rat isolated mesenteric artery rings pre-contracted by phenylephrine ...

a micro-channel heat exchanger reactor with different micro-baffle shapes has been studied numerically. governing equations were solved base on the finite volume method with fluent software. in upper section, oxidation reaction of methanol was occurred and in lower section, steam reforming of methanol was done. two sections were separated with solid part which played as heat exchanger and trans...

one of the really important challenges facing agricultural producers is the choice of their product distribution channels. the present study is aimed at investigating the citrus marketing channel strategy and its determinants among citrus orchardists of mazandaran using a nested logit model. some two hundred and fifty two orchardists from 15 cities of mazandaran were taken as the study samples....

this paper presents the results of a numerical study on the heat transfer performance and the removal process of fluid particles under the influence of magnetohydrodynamic mixed convection in a horizontal channel with an open cavity. the bottom wall of the cavity is heated at a constant temperature (th) while the top wall of the channel is maintained at a relatively low temperature (tc). air wi...

the advent of e-commerce has prompted many manufacturers to redesign their traditional channel structure by engaging in direct sales. in this paper, we present a dual channel inventory model based on queuing theory in a manufacturer-retailer supply chain, consisting of a traditional retail channel and a direct channel which stocks are kept in both upper and lower echelon. the system receives st...

the goal of this study was to determine the effects of the l-type calcium channel blockers verapamil and diltiazem on the currents of voltage-gated potassium channel (fkv1.4δn), an n-terminal-deleted mutant of the ferret kv1.4 potassium channel. measurements were made using a two electrode voltage clamp technique with channels expressed stably in xenopus oocytes. the fkv1.4δn currents displayed...

This study makes use of the Tsallis entropy to predict the shear stress distribution. Given a definition of the Tsallis entropy, it is maximized by using the probability density function, which then is used to attain a novel shear stress equation. This is then employed for calculating the shear stress distribution in rectangular channels in different aspect ratios and finally, for viability, th...

objective(s): recently, phthalimide derivatives were designed based on ameltolide and thalidomide as they possess a similar degree of anticonvulsant potency due to their phenytoin-like profile. the ability of phthalimide pharmacophore to interact with neuronal voltage-dependent sodium channels was studied in the batrachotoxin affinity assay. therefore, in the present study, a series of 19 compo...

In this study, we introduce a new two-way relay channel and obtain an inner bound and an outer bound for the discrete and memoryless multiple access relay channels with receiver-source feedback via two-way relay channel in which end nodes exchange signals by a relay node. And we extend these results to the Gaussian case. By numerical computing, we show that our inner bound is the same with o...

In an environment such as underwater channel where placing test equipments are difficult to handle, it is much practical to have hardware simulators to examine suitably designed transceivers (transmitter/receiver). The simulators of this kind will then allow researchers to observe their intentions and carry out repetitive tests to find suitable digital coding/decoding algorithms. In this p...