Although there are general guidelines on endoscopic biopsy for diagnosing gastric neoplasms, they are predominantly based on outdated literature obtained with fiberscopes without analyses specific to tumor characteristics.This study aims to comprehensively characterize the contemporary endoscopic biopsy by determining the diagnostic yield across different lesion morphologies and histological st...

BACKGROUND Altered expression of lamins A/C and B1, constituent proteins of the nuclear lamina, may occur during differentiation and has also been reported in primary lung cancer. AIMS To examine the expression of these proteins in gastrointestinal neoplasms. PATIENTS Archival human paraffin wax blocks and frozen tissue from patients undergoing surgical resection or endoscopic biopsy. MET...

Although it can affect any part of the gastrointestinal system, signet ring cell carcinoma (SRC) is a common malignant entity stomach cancers. We discuss case patient who had prior history gastric adenocarcinoma with cells, for which he underwent partial gastrectomy gastro-jejunal anastomosis. Four months after surgery, presented an acute postoperative blockage. Operative findings and pathology...

Background Gastrointestinal stromal tumors are mesenchymal neoplasms of the gastrointestinal tract, arising from the muscular layer. Revent immunohistochemical studies have shown that up to 94% of GISTs express 117, and 60–70% of GISTs stain for CD 34. GISTs account for 1% of all malignant tumors of gastrointestinal tract; they arise from stomach in the 40–60% of cases whereas they account only...

Gastrointestinal stromal tumors (GISTs) represent the majority of primary non-epithelial neoplasms of the digestive tract, most frequently expressing the KIT protein detected by immunohistochemical staining for the CD117 antigen. Extragastrointestinal stromal tumors (EGISTs), neoplasms with immunohistological features overlapping those of GISTs, are found in the abdomen outside of the gastroint...