AIM The aim of this study was estimation of clinical value of gastric tube esophagoplasty in children based on one single center experience. METHODS Forty-nine patients with diagnosis of EA (n=22) and caustic esophageal injury (n=27) had undergone reverse gastric tube esophagoplasty during 25 years at our institution. Almost all EA patients received initially gastrostomy and cervical esophago...

BACKGROUND Guidelines for fasting in elderly patients with acute hip fracture are the same as for other trauma patients, and longer than for elective patients. The reason is assumed stress-induced delayed gastric emptying with possible risk of pulmonary aspiration. Prolonged fasting in elderly patients may have serious negative metabolic consequences. The aim of our study was to investigate whe...

Wernicke encephalopathy consists of a triad of ophthalmoplegia, ataxia, and altered mental status. It is caused by thiamine deficiency and although it is commonly seen in alcoholics, patients undergoing gastric bypass surgery for morbid obesity could be a new group of patients to watch for. Florid papilloedema and optic neuropathy are not commonly seen but are still consistent with the diagnosi...

Aims: The objective of this retrospective study was to evaluate the prevalence Helicobacter pylori (H. pylori) positivity, gastric atrophy, and intestinal metaplasia in patients with dyspeptic complaints who had undergone total hip knee replacement surgeries, compared a control group without prosthesis.
 Methods: consisted 51 prosthesis, while comprised 75 similar but prosthesis. Endoscopi...

Objectives. Zollinger-Ellison Syndrome (ZES) results in hypersecretion of gastric acid (via gastrinoma) leading to peptic ulcers, diarrhea, and abdominal pain. We describe the novel discovery of hypertrophic, heterotopic gastric mucosa in the proximal duodenal bulb in patients with ZES, which we hypothesize results in an increased incidence of postbulbar ulcers in patients with ZES (a mechanism...

BACKGROUND/AIMS H. pylori CagL amino acid polymorphisms such as Y58/E59 can increase integrin α5β1 expression and gastric cancer risk. Hypochlorhydria during chronic H. pylori infection promotes gastric carcinogenesis. The study test whether CagL-Y58/E59 isolates may regulate integrin α5β1 to translocate CagA via the type IV secretory system even under adverse pH conditions, and whether the int...

Oesophageal replacement in patients following distal gastrectomy (DGE) remains a surgical challenge, and the standard option is the colonic or jejunal transplant. However, in some cases, it is possible (or mandatory) to utilize the remnant stomach for oesophagoplasty (EP). This method preserves some advantages of the gastric EP in comparison with the bowel EP. During recent years, several paper...

OBJECTIVE Slowing of gastric emptying by hyperglycemia, a physiological response to minimize postprandial hyperglycemia, may be impaired in patients with type 1 diabetes. The causes and consequences on glucose homeostasis are unknown. RESEARCH DESIGN AND METHODS Consequences of euglycemia- and hyperglycemia-induced changes in gastric emptying on postprandial glucose fluxes and excursions were...

Abstract Aim This project investigates whether patients received appropriate post-operative biochemical monitoring and micronutrient replacement after bariatric surgery, as per British Obesity & Metabolic Surgery Society (BOMSS) guidelines. Method A total of 27 Patients underwent either gastric bypass or sleeve gastrectomy between 1st August 2020 to 31st July 2021 at Northumbria Healthcare ...

OBJECTIVE To review the diagnosis and management of drug overdosage in a two-part presentation. DATA SOURCES A review of articles reported on drug overdose and poisoning. SUMMARY OF REVIEW A patient who has taken an overdose of a common drug often presents with an alteration in neurological, cardiovascular and respiratory functions. The differential diagnosis includes, central nervous syste...