Background & Aims: The aim of the present study was to find whether prone position is one of the symptoms of childhood gastroesophageal reflux disease or not. Method: In this prospective case-control study, 200 children with gastroesophgeal reflux disease (case group) and 210 healthy children (control group) were studied between 21 march 2009 and 21 march 2011. Data gathering was performed by a...

HYPOTHESIS There is an independent association between the different patterns of esophageal acid exposure in gastroesophageal reflux disease and the severity of the disease. DESIGN Case-comparison study. SETTING Department of surgery at a university hospital. PATIENTS A group of 401 patients with increased esophageal acid exposure divided into 4 groups according to the pattern of reflux: ...

CONTEXT Gastroesophageal reflux disease is a chronic disease in which gastroduodenal contents reflux into the esophagus. The clinical picture of gastroesophageal reflux disease is usually composed by heartburn and regurgitation (typical manifestations). Atypical manifestations (vocal disturbances and asthma) may also be complaint. OBJECTIVE To analyse the clinical, endoscopic, manometric and ...

There is a growing evidence that gastroesophageal reflux disease is related to several upper gastrointestinal cancers, mainly the esophageal adenocarcinoma and a certain type of gastric cardia adenocarcinoma. Currently, the incidence of gastroesophageal reflux disease is rapidly increasing in Korea. Therefore, there is a possibility of such increasing cancerous incidents, similar to the western...

updated guidelines for the diagnosis and treatment of gastroesophageal reflux disease

OBJECTIVES To ascertain the prevalence of Helicobacter pylori in patients with gastro-oesophageal reflux disease and its association with the disease. DESIGN Systematic review of studies reporting the prevalence of H pylori in patients with and without gastro-oesophageal reflux disease. DATA SOURCES Four electronic databases, searched to November 2001, experts, pharmaceutical companies, and...

The incidence and prevalence of gastro-oesophageal reflux disease is rising. Changing dietary habits and increasing body weight can be held responsible. In several studies a close relation was found between body weight and the occurrence of reflux disease. It may be concluded that there is a definite relation between body mass index and the occurrence of reflux disease. H. pylori probably also ...

HYPOTHESIS Traditionally, patients with gastroesophageal reflux disease fall into 3 categories based on 24-hour pH testing and the clinical occurrence of their acid exposure. Patients with upright reflux are believed to do worse following surgery compared with supine or bipositional reflux patients. We assessed objective postoperative outcomes for patients with upright, supine, and bipositional...