CONTEXT Esophageal pH monitoring is considered to be the gold standard for the diagnosis of gastroesophageal acid reflux. However, this method is very troublesome and considerably limits the patient's routine activities. Wireless pH monitoring was developed to avoid these restrictions. OBJECTIVE To compare the first 24 hours of the conventional and wireless pH monitoring, positioned 3 cm abov...

(or the treatment of gastroesophageal reflux) and outcomes in IPF. Patients taking oral antiacid therapy appear to have a slower rate of decline in lung function [5] and improved survival [6] . In addition, there is evidence suggesting that gastroesophageal reflux may be an important cause of acute exacerbation [5, 7–8] . Both acid and nonacid reflux might play an important role, and in this re...

BACKGROUND Asthma, laryngitis and chronic cough are atypical symptoms of the gastroesophageal reflux disease. AIM To analyze the efficacy of laparoscopic surgery in the remission of extra-esophageal symptoms in patients with gastroesophageal reflux, related to asthma. METHODS Were reviewed the medical records of 400 patients with gastroesophageal reflux disease submitted to laparoscopic Nis...

CONTEXT Currently, thickened feeds are increasingly being used to treat infants with gastroesophageal reflux, driven in large part by the baby food industry. Previous meta-analyses have shown that although thickened formulas do not seem to reduce measurable reflux, they may reduce vomiting. However, because data are limited, there is still uncertainty regarding the use of thickening agents. O...

Background Gastroesophageal Reflux is a physiological phenomenon, which occurs in infants, children, and normal adults. Various studies have shown that Baclofen is a potent inhibitor of lower esophageal sphincter and has beneficial effects in adult reflux disease. We aimed to evaluate the Baclofen effect in pediatric Gastroesophage...

BACKGROUND Gastroesophageal reflux is overrepresented in people with obstructive sleep apnea (OSA) and it has been suggested that OSA worsens gastroesophageal reflux symptoms. Aggravated reflux might lead to an increased risk of Barrett's esophagus. AIM To assess the association between sleep apnea symptoms and Barrett's esophagus. METHODS Included in a case-control study in Brisbane, Austr...

BACKGROUND Increasing numbers of infants are receiving prescription medications for symptoms associated with gastroesophageal reflux. Our aim was to prospectively measure reported gastroesophageal reflux symptoms in healthy term infants for the first six months of life. METHODS In a prospective cohort study in the rural Upper Peninsula of Michigan, 128 consecutive maternal-infant pairs were f...

Esophageal (EA) and esophagogastric junction (EGJA) adenocarcinoma have been steadily increasing in frequency in younger people; however, the etiology of these cancers is poorly understood. We therefore investigated associations of body mass index (BMI), cigarette smoking, alcohol consumption, gastroesophageal reflux and use of nonsteroidal anti-inflammatory drugs (NSAIDs) in relation to age-sp...

BACKGROUND/AIMS Rikkunshito (TJ-43), an herbal medicine, has been demonstrated to relieve gastroesophageal reflux symptoms. However, the effects of TJ-43 on esophageal motor functions have not been fully determined. This double-blind crossover study was performed to investigate the effects of TJ-43 on esophageal motor functions and gastroesophageal reflux. METHODS The subjects were 10 normal ...