Gaucher disease (GD) is characterized by accumulation of glucosylceramide (GC) in the cells of monocyte/macrophage system. The degradation of GC is controlled by glucosylceramidase (GCase) and saposin (Sap) C, a member of a family of four small glycoproteins (Saps A, B, C and D), all derived by proteolytic processing of a common precursor, prosaposin (PSAP). Saps contain six cysteine residues, ...

This study reports the flicker noise characteristics in GaAs-based MOSFETs for the first time. With the improvement in Ga 2 O 3 (Gd 2 O 3) insulators, GaAs MOSFETs reveal the possibility for high-speed and high-power applications, resulting from an electronic mobility that is about five times greater than that in Si, and the advantage of semi-insulating substrate. The DC and RF characteristics ...

the mononuclear gd(iii) complex, [gd(l)3(h2o)5] (where l is alizarin yellow r (nac13h8n3o5)), has been prepared in h2o under reflux condition. the gd(iii) complex has been characterized by elemental analysis and spectroscopic methods (uv–vis and ft–ir). the gd2o3 nanoparticles were prepared by the calcination of the gd(iii) complex in air at different temperatures up to 600 °c for 2 h. the calc...

Novel photocatalysts Gd₂FeSbO₇, Gd₂InSbO₇ and Gd₂YSbO₇ were synthesized by the solid state reaction method for the first time. A comparative study about the structural and photocatalytic properties of Gd₂MSbO₇ (M = Fe, In, Y) was reported. The results showed that Gd₂FeSbO₇, Gd₂InSbO₇ and Gd₂YSbO₇ crystallized with the pyrochlore-type structure, cubic crystal system and space group Fd3m. The lat...

The eigenvalues of the isotropic magnetic interaction system extraction from Internal Field Approximation (IFA) q e computed. on the basis of RKKY for the complicated magnetic behaviour of Gd, X system X= (Au , Pt , Al , In ) as well as Gd. From the strength and slope of eigenvalue curves in different ranges of interaction the strength and sharpness of the magnetic transition can be suggest...

Let λKv be the complete multigraph with v vertices, where any two distinct vertices x and y are joined by λ edges {x, y}. Let G be a finite simple graph. A G-design of λKv, denoted by (v,G, λ)-GD, is a pair (X,B), where X is the vertex set of Kv and B is a collection of subgraphs of Kv, called blocks, such that each block is isomorphic to G and any two distinct vertices in Kv are joined in exac...

Classical Brill-Noether theory studies, for given g, r, d, the space of line bundles of degree d with r + 1 global sections on a curve of genus g. After reviewing the main results in this theory, and the role of degeneration techniques in proving them, we will discuss the situation for higher-rank vector bundles, where even the most basic questions remain wide open. Focusing on the case of rank...

Herpes simplex virus 1 mutants lacking the gene encoding glycoprotein D (gD) and the gD normally present in the envelope of the virus (gD(-/-) stocks) or mutants lacking the gD gene but containing trans-induced gD in their envelopes (gD(-/+)) cause apoptosis in human SK-N-SH cells. The gD(-/-) virions are taken up by endocytosis and are degraded, whereas gD(-/+) viruses replicate but produce gD...