نتایج جستجو برای: gene expression analysis

تعداد نتایج: 4082624  

Journal: :The Journal of Animal Genetics 2019

Journal: :مجله علوم اعصاب شفای خاتم 0
mehrnaz banazadeh dardashti shefa neuroscience research center, khatam alanbia hospital, tehran, iran. milad ahmadi shefa neuroscience research center, khatam alanbia hospital, tehran, iran. hassan hosseini ravandi shefa neuroscience research center, khatam alanbia hospital, tehran, iran.

genetic epidemiological studies strongly suggest that additive and interactive genes, each with small effects, mediate the genetic vulnerability for schizophrenia. with the human genome working draft at hand, candidate gene (and ultimately large-scale genome-wide) association studies are gaining renewed interest in the effort to unravel the complex genetics of schizophrenia. linkage and fine ma...

Journal: :novelty in biomedicine 0
mehdi azad department of medical laboratory sciences, faculty of allied medicine, qazvin university of medical sciences, qazvin, iran mehdi goudarzi department of microbiology, school of medicine, shahid beheshti university of medical sciences mehdi sahmani department of clinical biochemistry and genetics, cellular and molecular research centre, qazvin university of medical sciences, qazvin, iran ali dehghanifard sarem cell research center, sarem women’s hospital, tehran, iran naser mobarra 5department of biochemistry and biophysics, metabolic disorders research center, school of medicine, golestan university of medical sciences, gorgan, iran mousa vatanmakanian department of hematology, allied medical school, tehran university of medical sciences, tehran, iran

background: several influential factors such as transcription factors and intracellular signaling components are involved in differentiation of stem cells into a specific lineage. p15 and p16 proteins are among these factors. accumulating evidences has introduced the epigenetic as a master regulator of these factors during lineage specification. the main objective of this study is to determine ...

Journal: :journal of biotechnology and health sciences 0
afshin rostami plant protection department, university of zanjan, zanjan, ir iran; plant protection department, university of zanjan, zanjan, ir iran. tel/fax: +98-2632238529 nemat sokhandan bashir plant protection department, university of tabriz, tabriz, ir iran davood koolivand plant protection department, university of zanjan, zanjan, ir iran mohammad hajizadeh plant protection department, university of kurdistan, sanandaj, ir iran

conclusions this is the first report of expression of cmv cp gene in iran, which is important for the preparation of anti-cmv antibody and paving the way for the use of the virus coat protein as a nanomaterial. results the identity of the expressed protein was confirmed by immunoassays such as western blot, dot-immunobinding assay (diba) and enzyme-linked immunosorbent assay (elisa) by the use ...

Journal: :iranian biomedical journal 0
فاطمه خردمند fatemeh kheradmand عیسی نورمحمدی issa nourmohammadi محمد حسین مدرسی mohammad hossein modarressi محسن فیروزرای mohsen firoozrai محمد امین احمدی فقیه mohammad amin ahmadi-faghih

background: zinc (zn) as an important trace element is essential for testicular development and spermatogenesis. molecular mechanism of zn action in the reproductive system may be related to metal binding low-molecular weight proteins, metallothioneins (mt). our objective was to determine the effect of zn on two important isoforms of mt, mt1m and mt1g genes expression on testicular sertoli cell...

Journal: :iranian journal of basic medical sciences 0
maryam rastin immunology research center, buali research institute, faculty of medicine, mashhad university of medical sciences, mashhad, iran mahmoud mahmoudi immunology research center, buali research institute, faculty of medicine, mashhad university of medical sciences, mashhad, iran mohammadreza hatef 2rheumatology research center, imam reza hospital, faculty of medicine, mashhad university of medical sciences, mashhad, iran maryam sahebari 3rheumatology research center, ghaem hospital, faculty of medicine, mashhad university of medical sciences, mashhad, iran nafiseh tabasi 1immunology research center, buali research institute, faculty of medicine, mashhad university of medical sciences, mashhad, iran dariush haghmorad 1immunology research center, buali research institute, faculty of medicine, mashhad university of medical sciences, mashhad, iran

objective(s):  apoptosis is a tightly regulated process and plays a crucial role in autoimmune diseases. because abnormalities in apoptosis are considered to be involved in the pathogenesis of systemic lupus erythematosus (sle), in present study we studied the apoptosis in t lymphocytes from iranian sle patientsat protein and gene expression levels for some molecules which are involved in apopt...

Journal: :iranian journal of pharmaceutical sciences 0
mohsen imanshahidi faculty of pharmacy, mashhad university of medical sciences, mashhad, iran

extracellular ca 2+ concentration ([ca2+]o) may be one of the factors affecting atrial natriuretic factor (anf) release. in the previous studies, there are opposite reports about the effect of [ca2+]o on anf secretion. therefore, the effect of [ca2+]o depletion on anf secretion and gene expression was studied in the present research. isolated right atria from rats were perfused for 6 and 2 hour...

ژورنال: پژوهش در پزشکی 2017

Background: the breast cancer is the second cause of worldwide death. Understanding of molecular pathology of breast cancer can provide useful information about new treatment routes. HER4 gene considered as a molecular pre-prognostic marker in cancers recently. So the purpose of this research is studying of HER4 gene expression in breast cancer patients. Methods: in this study 70 samples of ...

Journal: :iranian journal of public health 0
maryam farhadian 1. dept. of epidemiology & biostatistics, school of public health, hamadan university of medical sciences , hamadan. iran . hossein mahjub 2. research center for health sciences and dept. of epidemiology & biostatistics, school of public health, hamadan university of medical sciences , hamadan, iran. abbas moghimbeigi 3. modeling of noncommunicable diseases research center and dept. of epidemiology & biostatistics, school of public health, hamadan university of medical sciences , hamadan, iran. jalal poorolajal 3. modeling of noncommunicable diseases research center and dept. of epidemiology & biostatistics, school of public health, hamadan university of medical sciences , hamadan, iran. muharram mansoorizadeh 4. dept. of computer engineering, faculty of engineering, bu-ali sina university , hamadan, iran.

an important aspect of microarray studies includes the prediction of patient survival based on their gene expression profile. to deal with the high dimensionality of this data, use of a dimension reduction procedure along with the survival prediction model is necessary. this study aimed to present a new method based on wavelet transform for survival relevant gene selection.the data included 204...

Introduction: Oxygen tension is one of the most important stimuli in stem cell biology. In this study, we investigate the considerable influence of hypoxia on CX43 gene expression as one of the most important gap junction on the surface of mesenchymal stem cells. Methods: Mesenchymal stem cells were isolated from C57BL/6 mouse bone marrow and cultured in DMEM medium under low oxygen tension (...

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